SNAP-25 in hippocampal CA3 region is required for long-term memory formation

SNAP-25 is a synaptosomal protein of 25 kDa, a key component of synaptic vesicle-docking/fusion machinery, and plays a critical role in exocytosis and neurotransmitter release. We previously reported that SNAP-25 in the hippocampal CA1 region is involved in consolidation of contextual fear memory an...

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Veröffentlicht in:	Biochemical and biophysical research communications 2006-09, Vol.347 (4), p.955-962
Hauptverfasser:	Hou, Qiu-Ling, Gao, Xiang, Lu, Qi, Zhang, Xue-Han, Tu, Yan-Yang, Jin, Mei-Lei, Zhao, Guo-Ping, Yu, Lei, Jing, Nai-He, Li, Bao-Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Animals BRAIN Conditioning (Psychology) - drug effects Conditioning (Psychology) - physiology Fear - physiology HIPPOCAMPUS Hippocampus - anatomy & histology Hippocampus - drug effects INFUSION Long-term potentiation Long-Term Potentiation - drug effects Long-Term Potentiation - radiation effects Male Memory Memory - physiology OLIGONUCLEOTIDES Oligonucleotides, Antisense - pharmacology PROTEINS Rat RATS Rats, Sprague-Dawley SNAP-25 Spatial Behavior - drug effects Spatial Behavior - radiation effects Synaptosomal-Associated Protein 25 - physiology
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