Parietal endoderm secreted S100A4 promotes early cardiomyogenesis in embryoid bodies

Cardiomyogenesis is influenced by factors secreted by anterior-lateral and extra-embryonic endoderm. Differentiation of embryonic stem cells in embryoid bodies allows to study the influence of growth factors on cardiomyogenesis. By these means SPARC was identified as a new factor enhancing cardiomyo...

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Veröffentlicht in:	Biochemical and biophysical research communications 2006-05, Vol.343 (2), p.555-563
Hauptverfasser:	Stary, Martina, Schneider, Mikael, Sheikh, Søren P., Weitzer, Georg
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES CALCIUM Cardiomyocytes Cardiomyogenesis Cell Differentiation - drug effects Cell Line CELL PROLIFERATION Dose-Response Relationship, Drug Embryo, Mammalian - cytology Embryo, Mammalian - drug effects Embryo, Mammalian - physiology Embryoid bodies Embryonic stem cells Endoderm - secretion GENES GROWTH FACTORS Homeobox Protein Nkx-2.5 Homeodomain Proteins - metabolism Humans IN VITRO MADS Domain Proteins - metabolism MEF2 Transcription Factors Myocytes, Cardiac - cytology Myocytes, Cardiac - drug effects Myocytes, Cardiac - physiology Myogenic Regulatory Factors - metabolism S100 Calcium-Binding Protein A4 S100 Proteins - administration & dosage S100 Proteins - secretion S100A4 STEM CELLS TRANSCRIPTION TRANSCRIPTION FACTORS Transcription Factors - metabolism
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