Diabetic mice are protected from normally lethal nephrotoxicity of S-1,2-dichlorovinyl- l-cysteine (DCVC): role of nephrogenic tissue repair

Streptozotocin (STZ)-induced diabetic (DB) rats are protected from nephrotoxicity of gentamicin, cisplatin and mercuric chloride, although the mechanisms remain unclear. Ninety percent of DB mice receiving a LD90 dose (75 mg/kg, ip) of S-1,2-dichlorovinyl- l-cysteine (DCVC) survived in contrast to o...

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