Asian sand dust enhances ovalbumin-induced eosinophil recruitment in the alveoli and airway of mice
Asian sand dust (ASD) containing sulfate (SO 4 2−) reportedly causes adverse respiratory health effects but there is no experimental study showing the effect of ASD toward allergic respiratory diseases. The effects of ASD and ASD plus SO 4 2− toward allergic lung inflammation induced by ovalbumin (O...
Gespeichert in:
| Veröffentlicht in: | Environmental research 2005-11, Vol.99 (3), p.361-368 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 368 |
|---|---|
| container_issue | 3 |
| container_start_page | 361 |
| container_title | Environmental research |
| container_volume | 99 |
| creator | Hiyoshi, Kyoko Ichinose, Takamichi Sadakane, Kaori Takano, Hirohisa Nishikawa, Masataka Mori, Ikuko Yanagisawa, Rie Yoshida, Seiichi Kumagai, Yoshito Tomura, Shigeo Shibamoto, Takayuki |
| description | Asian sand dust (ASD) containing sulfate (SO
4
2−) reportedly causes adverse respiratory health effects but there is no experimental study showing the effect of ASD toward allergic respiratory diseases. The effects of ASD and ASD plus SO
4
2− toward allergic lung inflammation induced by ovalbumin (OVA) were investigated in this study. ICR mice were administered intratracheally with saline; ASD alone (sample from Shapotou desert); and ASD plus SO
4
2− (ASD-SO
4); OVA+ASD; OVA+ASD-SO
4. ASD or ASD-SO
4 alone caused mild nutrophilic inflammation in the bronchi and alveoli. ASD and ASD-SO
4 increased pro-inflammatory mediators, such as Keratinocyte chemoattractant (KC) and macrophage inflammatory protein (MIP)-1 alpha, in bronchoalveolar lavage fluids (BALF). ASD and ASD-SO
4 enhanced eosinophil recruitment induced by OVA in the alveoli and in the submucosa of the airway, which has a goblet cell proliferation in the bronchial epithelium. However, a further increase of eosinophils by addition of SO
4
2− was not observed. The two sand dusts synergistically increased interleukin-5 (IL-5) and monocyte chemotactic protein-1 (MCP-1), which were associated with OVA, in BALF. However, the increased levels of IL-5 were lower in the OVA+ASD-SO
4 group than in the OVA+ASD group. ASD caused the adjuvant effects to specific-IgG1 production by OVA, but not to specific-IgE. These results suggest that the enhancement of eosinophil recruitment in the lung is mediated by synergistically increased IL-5 and MCP-1. IgG1 antibodies may play an important role in the enhancement of allergic reaction caused by OVA and sand dust. However, extra sulfate may not contribute to an increase of eosinophils. |
| doi_str_mv | 10.1016/j.envres.2005.03.008 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_osti_</sourceid><recordid>TN_cdi_osti_scitechconnect_20775317</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0013935105000319</els_id><sourcerecordid>17454027</sourcerecordid><originalsourceid>FETCH-LOGICAL-c515t-295795ab5b4fad0802e98b9dc7f4576048341d96e07de1f4e0597b13f7c588e83</originalsourceid><addsrcrecordid>eNp9kU2L1TAUhoMoznX0H4gERHetJ03TNBthGPyCATe6Dmlyys2lTa5Je2X-vSm9MDtX4cBzXnLeh5C3DGoGrPt0qjFcEua6ARA18Bqgf0YODFRXgRL8OTkAMF4pLtgNeZXzqYxMcHhJbljHQSrZH4i9y94Emk1w1K15oRiOJljMNF7MNKyzD5UPbrXoKMbsQzwf_UQT2rT6ZcawUB_ockRqpgvGydMtyfj01zzSONLZW3xNXoxmyvjm-t6S31-__Lr_Xj38_Pbj_u6hsoKJpWqUkEqYQQztaBz00KDqB-WsHFshO2h73jKnOgTpkI0tglByYHyUVvQ99vyWvN9zY168ztYvaI82hoB20Q1IKTiThfq4U-cU_6yYFz37bHGaTMC4Zs1kK1poNrDdQZtizglHfU5-NulRM9CbAn3SuwK9KdDAdVFQ1t5d89dhRve0dO28AB-ugMnWTGMqffv8xEnOW9Wrwn3eOSydXTym7SQsbpxP20Uu-v__5B8AjKZ8</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>17454027</pqid></control><display><type>article</type><title>Asian sand dust enhances ovalbumin-induced eosinophil recruitment in the alveoli and airway of mice</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Hiyoshi, Kyoko ; Ichinose, Takamichi ; Sadakane, Kaori ; Takano, Hirohisa ; Nishikawa, Masataka ; Mori, Ikuko ; Yanagisawa, Rie ; Yoshida, Seiichi ; Kumagai, Yoshito ; Tomura, Shigeo ; Shibamoto, Takayuki</creator><creatorcontrib>Hiyoshi, Kyoko ; Ichinose, Takamichi ; Sadakane, Kaori ; Takano, Hirohisa ; Nishikawa, Masataka ; Mori, Ikuko ; Yanagisawa, Rie ; Yoshida, Seiichi ; Kumagai, Yoshito ; Tomura, Shigeo ; Shibamoto, Takayuki</creatorcontrib><description>Asian sand dust (ASD) containing sulfate (SO
4
2−) reportedly causes adverse respiratory health effects but there is no experimental study showing the effect of ASD toward allergic respiratory diseases. The effects of ASD and ASD plus SO
4
2− toward allergic lung inflammation induced by ovalbumin (OVA) were investigated in this study. ICR mice were administered intratracheally with saline; ASD alone (sample from Shapotou desert); and ASD plus SO
4
2− (ASD-SO
4); OVA+ASD; OVA+ASD-SO
4. ASD or ASD-SO
4 alone caused mild nutrophilic inflammation in the bronchi and alveoli. ASD and ASD-SO
4 increased pro-inflammatory mediators, such as Keratinocyte chemoattractant (KC) and macrophage inflammatory protein (MIP)-1 alpha, in bronchoalveolar lavage fluids (BALF). ASD and ASD-SO
4 enhanced eosinophil recruitment induced by OVA in the alveoli and in the submucosa of the airway, which has a goblet cell proliferation in the bronchial epithelium. However, a further increase of eosinophils by addition of SO
4
2− was not observed. The two sand dusts synergistically increased interleukin-5 (IL-5) and monocyte chemotactic protein-1 (MCP-1), which were associated with OVA, in BALF. However, the increased levels of IL-5 were lower in the OVA+ASD-SO
4 group than in the OVA+ASD group. ASD caused the adjuvant effects to specific-IgG1 production by OVA, but not to specific-IgE. These results suggest that the enhancement of eosinophil recruitment in the lung is mediated by synergistically increased IL-5 and MCP-1. IgG1 antibodies may play an important role in the enhancement of allergic reaction caused by OVA and sand dust. However, extra sulfate may not contribute to an increase of eosinophils.</description><identifier>ISSN: 0013-9351</identifier><identifier>EISSN: 1096-0953</identifier><identifier>DOI: 10.1016/j.envres.2005.03.008</identifier><identifier>PMID: 16307978</identifier><identifier>CODEN: ENVRAL</identifier><language>eng</language><publisher>Amsterdam: Elsevier Inc</publisher><subject>60 APPLIED LIFE SCIENCES ; Air ; Allergic inflammation ; Animals ; ANTIBODIES ; Asia ; Asian sand dust ; Biological and medical sciences ; BRONCHI ; Bronchoalveolar Lavage Fluid - chemistry ; Bronchoalveolar Lavage Fluid - immunology ; CELL PROLIFERATION ; Chemokine CCL2 - biosynthesis ; Dust - immunology ; DUSTS ; Environmental pollutants toxicology ; Eosinophil recruitment ; EOSINOPHILS ; Eosinophils - physiology ; EPITHELIUM ; Immunoglobulin G - analysis ; INFLAMMATION ; Interleukin-5 - biosynthesis ; ION CYCLOTRON-RESONANCE ; LUNGS ; MACROPHAGES ; Male ; Medical sciences ; MICE ; Mice, Inbred ICR ; MONOCYTES ; Murine lung ; OVA ; OVALBUMIN ; Pulmonary Alveoli - drug effects ; Pulmonary Alveoli - immunology ; SAND ; Silicon Dioxide ; SULFATES ; Sulfates - toxicity ; Toxicology</subject><ispartof>Environmental research, 2005-11, Vol.99 (3), p.361-368</ispartof><rights>2005 Elsevier Inc.</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c515t-295795ab5b4fad0802e98b9dc7f4576048341d96e07de1f4e0597b13f7c588e83</citedby><cites>FETCH-LOGICAL-c515t-295795ab5b4fad0802e98b9dc7f4576048341d96e07de1f4e0597b13f7c588e83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.envres.2005.03.008$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,315,781,785,886,3551,27929,27930,46000</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17334989$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16307978$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/20775317$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Hiyoshi, Kyoko</creatorcontrib><creatorcontrib>Ichinose, Takamichi</creatorcontrib><creatorcontrib>Sadakane, Kaori</creatorcontrib><creatorcontrib>Takano, Hirohisa</creatorcontrib><creatorcontrib>Nishikawa, Masataka</creatorcontrib><creatorcontrib>Mori, Ikuko</creatorcontrib><creatorcontrib>Yanagisawa, Rie</creatorcontrib><creatorcontrib>Yoshida, Seiichi</creatorcontrib><creatorcontrib>Kumagai, Yoshito</creatorcontrib><creatorcontrib>Tomura, Shigeo</creatorcontrib><creatorcontrib>Shibamoto, Takayuki</creatorcontrib><title>Asian sand dust enhances ovalbumin-induced eosinophil recruitment in the alveoli and airway of mice</title><title>Environmental research</title><addtitle>Environ Res</addtitle><description>Asian sand dust (ASD) containing sulfate (SO
4
2−) reportedly causes adverse respiratory health effects but there is no experimental study showing the effect of ASD toward allergic respiratory diseases. The effects of ASD and ASD plus SO
4
2− toward allergic lung inflammation induced by ovalbumin (OVA) were investigated in this study. ICR mice were administered intratracheally with saline; ASD alone (sample from Shapotou desert); and ASD plus SO
4
2− (ASD-SO
4); OVA+ASD; OVA+ASD-SO
4. ASD or ASD-SO
4 alone caused mild nutrophilic inflammation in the bronchi and alveoli. ASD and ASD-SO
4 increased pro-inflammatory mediators, such as Keratinocyte chemoattractant (KC) and macrophage inflammatory protein (MIP)-1 alpha, in bronchoalveolar lavage fluids (BALF). ASD and ASD-SO
4 enhanced eosinophil recruitment induced by OVA in the alveoli and in the submucosa of the airway, which has a goblet cell proliferation in the bronchial epithelium. However, a further increase of eosinophils by addition of SO
4
2− was not observed. The two sand dusts synergistically increased interleukin-5 (IL-5) and monocyte chemotactic protein-1 (MCP-1), which were associated with OVA, in BALF. However, the increased levels of IL-5 were lower in the OVA+ASD-SO
4 group than in the OVA+ASD group. ASD caused the adjuvant effects to specific-IgG1 production by OVA, but not to specific-IgE. These results suggest that the enhancement of eosinophil recruitment in the lung is mediated by synergistically increased IL-5 and MCP-1. IgG1 antibodies may play an important role in the enhancement of allergic reaction caused by OVA and sand dust. However, extra sulfate may not contribute to an increase of eosinophils.</description><subject>60 APPLIED LIFE SCIENCES</subject><subject>Air</subject><subject>Allergic inflammation</subject><subject>Animals</subject><subject>ANTIBODIES</subject><subject>Asia</subject><subject>Asian sand dust</subject><subject>Biological and medical sciences</subject><subject>BRONCHI</subject><subject>Bronchoalveolar Lavage Fluid - chemistry</subject><subject>Bronchoalveolar Lavage Fluid - immunology</subject><subject>CELL PROLIFERATION</subject><subject>Chemokine CCL2 - biosynthesis</subject><subject>Dust - immunology</subject><subject>DUSTS</subject><subject>Environmental pollutants toxicology</subject><subject>Eosinophil recruitment</subject><subject>EOSINOPHILS</subject><subject>Eosinophils - physiology</subject><subject>EPITHELIUM</subject><subject>Immunoglobulin G - analysis</subject><subject>INFLAMMATION</subject><subject>Interleukin-5 - biosynthesis</subject><subject>ION CYCLOTRON-RESONANCE</subject><subject>LUNGS</subject><subject>MACROPHAGES</subject><subject>Male</subject><subject>Medical sciences</subject><subject>MICE</subject><subject>Mice, Inbred ICR</subject><subject>MONOCYTES</subject><subject>Murine lung</subject><subject>OVA</subject><subject>OVALBUMIN</subject><subject>Pulmonary Alveoli - drug effects</subject><subject>Pulmonary Alveoli - immunology</subject><subject>SAND</subject><subject>Silicon Dioxide</subject><subject>SULFATES</subject><subject>Sulfates - toxicity</subject><subject>Toxicology</subject><issn>0013-9351</issn><issn>1096-0953</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU2L1TAUhoMoznX0H4gERHetJ03TNBthGPyCATe6Dmlyys2lTa5Je2X-vSm9MDtX4cBzXnLeh5C3DGoGrPt0qjFcEua6ARA18Bqgf0YODFRXgRL8OTkAMF4pLtgNeZXzqYxMcHhJbljHQSrZH4i9y94Emk1w1K15oRiOJljMNF7MNKyzD5UPbrXoKMbsQzwf_UQT2rT6ZcawUB_ockRqpgvGydMtyfj01zzSONLZW3xNXoxmyvjm-t6S31-__Lr_Xj38_Pbj_u6hsoKJpWqUkEqYQQztaBz00KDqB-WsHFshO2h73jKnOgTpkI0tglByYHyUVvQ99vyWvN9zY168ztYvaI82hoB20Q1IKTiThfq4U-cU_6yYFz37bHGaTMC4Zs1kK1poNrDdQZtizglHfU5-NulRM9CbAn3SuwK9KdDAdVFQ1t5d89dhRve0dO28AB-ugMnWTGMqffv8xEnOW9Wrwn3eOSydXTym7SQsbpxP20Uu-v__5B8AjKZ8</recordid><startdate>20051101</startdate><enddate>20051101</enddate><creator>Hiyoshi, Kyoko</creator><creator>Ichinose, Takamichi</creator><creator>Sadakane, Kaori</creator><creator>Takano, Hirohisa</creator><creator>Nishikawa, Masataka</creator><creator>Mori, Ikuko</creator><creator>Yanagisawa, Rie</creator><creator>Yoshida, Seiichi</creator><creator>Kumagai, Yoshito</creator><creator>Tomura, Shigeo</creator><creator>Shibamoto, Takayuki</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope><scope>OTOTI</scope></search><sort><creationdate>20051101</creationdate><title>Asian sand dust enhances ovalbumin-induced eosinophil recruitment in the alveoli and airway of mice</title><author>Hiyoshi, Kyoko ; Ichinose, Takamichi ; Sadakane, Kaori ; Takano, Hirohisa ; Nishikawa, Masataka ; Mori, Ikuko ; Yanagisawa, Rie ; Yoshida, Seiichi ; Kumagai, Yoshito ; Tomura, Shigeo ; Shibamoto, Takayuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c515t-295795ab5b4fad0802e98b9dc7f4576048341d96e07de1f4e0597b13f7c588e83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>60 APPLIED LIFE SCIENCES</topic><topic>Air</topic><topic>Allergic inflammation</topic><topic>Animals</topic><topic>ANTIBODIES</topic><topic>Asia</topic><topic>Asian sand dust</topic><topic>Biological and medical sciences</topic><topic>BRONCHI</topic><topic>Bronchoalveolar Lavage Fluid - chemistry</topic><topic>Bronchoalveolar Lavage Fluid - immunology</topic><topic>CELL PROLIFERATION</topic><topic>Chemokine CCL2 - biosynthesis</topic><topic>Dust - immunology</topic><topic>DUSTS</topic><topic>Environmental pollutants toxicology</topic><topic>Eosinophil recruitment</topic><topic>EOSINOPHILS</topic><topic>Eosinophils - physiology</topic><topic>EPITHELIUM</topic><topic>Immunoglobulin G - analysis</topic><topic>INFLAMMATION</topic><topic>Interleukin-5 - biosynthesis</topic><topic>ION CYCLOTRON-RESONANCE</topic><topic>LUNGS</topic><topic>MACROPHAGES</topic><topic>Male</topic><topic>Medical sciences</topic><topic>MICE</topic><topic>Mice, Inbred ICR</topic><topic>MONOCYTES</topic><topic>Murine lung</topic><topic>OVA</topic><topic>OVALBUMIN</topic><topic>Pulmonary Alveoli - drug effects</topic><topic>Pulmonary Alveoli - immunology</topic><topic>SAND</topic><topic>Silicon Dioxide</topic><topic>SULFATES</topic><topic>Sulfates - toxicity</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hiyoshi, Kyoko</creatorcontrib><creatorcontrib>Ichinose, Takamichi</creatorcontrib><creatorcontrib>Sadakane, Kaori</creatorcontrib><creatorcontrib>Takano, Hirohisa</creatorcontrib><creatorcontrib>Nishikawa, Masataka</creatorcontrib><creatorcontrib>Mori, Ikuko</creatorcontrib><creatorcontrib>Yanagisawa, Rie</creatorcontrib><creatorcontrib>Yoshida, Seiichi</creatorcontrib><creatorcontrib>Kumagai, Yoshito</creatorcontrib><creatorcontrib>Tomura, Shigeo</creatorcontrib><creatorcontrib>Shibamoto, Takayuki</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>OSTI.GOV</collection><jtitle>Environmental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hiyoshi, Kyoko</au><au>Ichinose, Takamichi</au><au>Sadakane, Kaori</au><au>Takano, Hirohisa</au><au>Nishikawa, Masataka</au><au>Mori, Ikuko</au><au>Yanagisawa, Rie</au><au>Yoshida, Seiichi</au><au>Kumagai, Yoshito</au><au>Tomura, Shigeo</au><au>Shibamoto, Takayuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Asian sand dust enhances ovalbumin-induced eosinophil recruitment in the alveoli and airway of mice</atitle><jtitle>Environmental research</jtitle><addtitle>Environ Res</addtitle><date>2005-11-01</date><risdate>2005</risdate><volume>99</volume><issue>3</issue><spage>361</spage><epage>368</epage><pages>361-368</pages><issn>0013-9351</issn><eissn>1096-0953</eissn><coden>ENVRAL</coden><abstract>Asian sand dust (ASD) containing sulfate (SO
4
2−) reportedly causes adverse respiratory health effects but there is no experimental study showing the effect of ASD toward allergic respiratory diseases. The effects of ASD and ASD plus SO
4
2− toward allergic lung inflammation induced by ovalbumin (OVA) were investigated in this study. ICR mice were administered intratracheally with saline; ASD alone (sample from Shapotou desert); and ASD plus SO
4
2− (ASD-SO
4); OVA+ASD; OVA+ASD-SO
4. ASD or ASD-SO
4 alone caused mild nutrophilic inflammation in the bronchi and alveoli. ASD and ASD-SO
4 increased pro-inflammatory mediators, such as Keratinocyte chemoattractant (KC) and macrophage inflammatory protein (MIP)-1 alpha, in bronchoalveolar lavage fluids (BALF). ASD and ASD-SO
4 enhanced eosinophil recruitment induced by OVA in the alveoli and in the submucosa of the airway, which has a goblet cell proliferation in the bronchial epithelium. However, a further increase of eosinophils by addition of SO
4
2− was not observed. The two sand dusts synergistically increased interleukin-5 (IL-5) and monocyte chemotactic protein-1 (MCP-1), which were associated with OVA, in BALF. However, the increased levels of IL-5 were lower in the OVA+ASD-SO
4 group than in the OVA+ASD group. ASD caused the adjuvant effects to specific-IgG1 production by OVA, but not to specific-IgE. These results suggest that the enhancement of eosinophil recruitment in the lung is mediated by synergistically increased IL-5 and MCP-1. IgG1 antibodies may play an important role in the enhancement of allergic reaction caused by OVA and sand dust. However, extra sulfate may not contribute to an increase of eosinophils.</abstract><cop>Amsterdam</cop><pub>Elsevier Inc</pub><pmid>16307978</pmid><doi>10.1016/j.envres.2005.03.008</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0013-9351 |
| ispartof | Environmental research, 2005-11, Vol.99 (3), p.361-368 |
| issn | 0013-9351 1096-0953 |
| language | eng |
| recordid | cdi_osti_scitechconnect_20775317 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | 60 APPLIED LIFE SCIENCES Air Allergic inflammation Animals ANTIBODIES Asia Asian sand dust Biological and medical sciences BRONCHI Bronchoalveolar Lavage Fluid - chemistry Bronchoalveolar Lavage Fluid - immunology CELL PROLIFERATION Chemokine CCL2 - biosynthesis Dust - immunology DUSTS Environmental pollutants toxicology Eosinophil recruitment EOSINOPHILS Eosinophils - physiology EPITHELIUM Immunoglobulin G - analysis INFLAMMATION Interleukin-5 - biosynthesis ION CYCLOTRON-RESONANCE LUNGS MACROPHAGES Male Medical sciences MICE Mice, Inbred ICR MONOCYTES Murine lung OVA OVALBUMIN Pulmonary Alveoli - drug effects Pulmonary Alveoli - immunology SAND Silicon Dioxide SULFATES Sulfates - toxicity Toxicology |
| title | Asian sand dust enhances ovalbumin-induced eosinophil recruitment in the alveoli and airway of mice |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-13T03%3A32%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_osti_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Asian%20sand%20dust%20enhances%20ovalbumin-induced%20eosinophil%20recruitment%20in%20the%20alveoli%20and%20airway%20of%20mice&rft.jtitle=Environmental%20research&rft.au=Hiyoshi,%20Kyoko&rft.date=2005-11-01&rft.volume=99&rft.issue=3&rft.spage=361&rft.epage=368&rft.pages=361-368&rft.issn=0013-9351&rft.eissn=1096-0953&rft.coden=ENVRAL&rft_id=info:doi/10.1016/j.envres.2005.03.008&rft_dat=%3Cproquest_osti_%3E17454027%3C/proquest_osti_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=17454027&rft_id=info:pmid/16307978&rft_els_id=S0013935105000319&rfr_iscdi=true |