Identification of contact and respiratory sensitizers using flow cytometry

Identification of the chemicals responsible for respiratory and contact allergies in the industrial area is an important occupational safety issue. This study was conducted in mice to determine whether flow cytometry is an appropriate method to analyze and differentiate the specific immune responses...

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Veröffentlicht in:	Toxicology and applied pharmacology 2005-06, Vol.205 (3), p.259-270
Hauptverfasser:	Goutet, Michèle, Pépin, Elsa, Langonné, Isabelle, Huguet, Nelly, Ban, Masarin
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Administration, Inhalation Administration, Topical Allergens - adverse effects Allergens - chemistry Allergens - immunology ALLERGY ANHYDRIDES Animals AUDITORY ORGANS Biological and medical sciences Contact and respiratory sensitizers Cytokines Cytokines - analysis Cytokines - metabolism Cytokines - secretion Dinitrochlorobenzene Dinitrochlorobenzene - adverse effects Dinitrochlorobenzene - chemistry Dinitrochlorobenzene - immunology Female Flow cytometry Flow Cytometry - methods Histocompatibility Antigens Class II - drug effects Histocompatibility Antigens Class II - genetics IgE Immunoglobulin E - blood Immunoglobulin E - immunology Local Lymph Node Assay LYMPH NODES Lymph Nodes - cytology Lymph Nodes - drug effects LYMPHOCYTES LYMPHOKINES Medical sciences MICE Mice, Inbred BALB C OCCUPATIONAL SAFETY Phthalic Anhydrides - adverse effects Phthalic Anhydrides - chemistry Phthalic Anhydrides - immunology RECEPTORS Receptors, Interleukin-4 - drug effects Receptors, Interleukin-4 - genetics SENSITIZERS Th subsets Time Factors Toxicology Trimellitic anhydride
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