Scanning electron microscopy study of neutrophil membrane tubulovesicular extensions (cytonemes) and their role in anchoring, aggregation and phagocytosis. The effect of nitric oxide

We have shown that human neutrophils develop dynamic thin and very long tubulovesicular extensions (cytonemes) upon adhesion to fibronectin, if cell spreading was blocked by Na +-free medium or by 4-bromophenacyl bromide, N-ethylmaleimide, 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and cytochalasin D (S...

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Veröffentlicht in:	Experimental cell research 2005-04, Vol.304 (2), p.620-629
Hauptverfasser:	Galkina, Svetlana I., Molotkovsky, Julian G., Ullrich, Volker, Sud'ina, Galina F.
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Adhesion ARGININE Boron Compounds - pharmacology Cell Adhesion - drug effects Cell Adhesion - physiology Cell Adhesion Molecules - metabolism Cell Aggregation - drug effects Cell Aggregation - physiology Cell Surface Extensions - drug effects Cell Surface Extensions - metabolism Cell Surface Extensions - ultrastructure Cytonemes Enzyme Inhibitors - pharmacology ERYTHROCYTES ESTERS Exocytosis - physiology Golgi complex Heparitinase Humans l-selectin Membrane tubulovesicular extensions Microscopy, Electron, Scanning Neutrophil (polymorphonuclear leukocyte) NEUTROPHILS Neutrophils - drug effects Neutrophils - metabolism Neutrophils - ultrastructure NITRIC OXIDE Nitric Oxide - pharmacology Nitric Oxide - physiology Nitric Oxide Donors - pharmacology Nitric Oxide Synthase - antagonists & inhibitors Nitric Oxide Synthase - metabolism OMEGA BARYONS Organelles - drug effects Organelles - metabolism Organelles - ultrastructure PHAGOCYTOSIS Phagocytosis - drug effects Phagocytosis - physiology SCANNING ELECTRON MICROSCOPY Signal Transduction - drug effects Signal Transduction - physiology Spreading β1 and β2 integrin
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