Vascular brachytherapy after percutaneous transluminal angioplasty of superficial femoral arteries—Polish pilot group
Purpose: The article presents the results of treatment with vascular brachytherapy (VBT) in superficial femoral arteries. This method aims to minimize frequency of restenosis after percutaneous transluminal angioplasty (PTA). Method: Treatment was carried out in 20 cases. The patients with severe st...
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description | Purpose: The article presents the results of treatment with vascular brachytherapy (VBT) in superficial femoral arteries. This method aims to minimize frequency of restenosis after percutaneous transluminal angioplasty (PTA).
Method: Treatment was carried out in 20 cases. The patients with severe stenoses or total occlusions verified in angiography were selected. In the group of 19 patients, two were women (the average age of the patients was 58.7 years). VBT was performed immediately after PTA. A 15-Gy dose, with high dose rate, was applied. The dose was calculated based on individually chosen distance from the internal surface of the artery wall, which varied from 2 to 3 mm. The mean observation time after treatment was 8 months. The shortest time was 1 month and the longest 14 months. At the end of the observation time, the control DSA angiography was performed on every patient.
Results: During the first 2 months, in three cases, an acute thrombosis in treated artery was observed. In the third month, one treated artery occluded. In the sixth month of observation, one case of acute thrombosis was observed. The rest of the patients were free of restenoses.
Conclusions: (1) In superficial femoral arteries, a low value of ankle brachial pressure index (ABPI; below 0.4) is very probably responsible for acute thrombosis after PTA with or without stent implantation followed by VBT. (2) Diabetes, rest ischaemia before treatment, poor vessel status confirmed in angiography may also be responsible for acute thrombosis after VBT. (3) Anticoagulants or antiplatelet (ticlipidine) treatment must be ordered for 6 months after VBT in patients with implanted stents. |
doi_str_mv | 10.1016/S1522-1865(02)00148-8 |
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Method: Treatment was carried out in 20 cases. The patients with severe stenoses or total occlusions verified in angiography were selected. In the group of 19 patients, two were women (the average age of the patients was 58.7 years). VBT was performed immediately after PTA. A 15-Gy dose, with high dose rate, was applied. The dose was calculated based on individually chosen distance from the internal surface of the artery wall, which varied from 2 to 3 mm. The mean observation time after treatment was 8 months. The shortest time was 1 month and the longest 14 months. At the end of the observation time, the control DSA angiography was performed on every patient.
Results: During the first 2 months, in three cases, an acute thrombosis in treated artery was observed. In the third month, one treated artery occluded. In the sixth month of observation, one case of acute thrombosis was observed. The rest of the patients were free of restenoses.
Conclusions: (1) In superficial femoral arteries, a low value of ankle brachial pressure index (ABPI; below 0.4) is very probably responsible for acute thrombosis after PTA with or without stent implantation followed by VBT. (2) Diabetes, rest ischaemia before treatment, poor vessel status confirmed in angiography may also be responsible for acute thrombosis after VBT. (3) Anticoagulants or antiplatelet (ticlipidine) treatment must be ordered for 6 months after VBT in patients with implanted stents.</description><identifier>ISSN: 1522-1865</identifier><identifier>DOI: 10.1016/S1522-1865(02)00148-8</identifier><identifier>PMID: 12479908</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Acute thrombosis ; Aged ; Angioplasty, Balloon ; ANTICOAGULANTS ; Arterial Occlusive Diseases - complications ; Arterial Occlusive Diseases - epidemiology ; Arterial Occlusive Diseases - therapy ; ARTERIES ; BIOMEDICAL RADIOGRAPHY ; Blood Vessel Prosthesis Implantation ; BRACHYTHERAPY ; DOSE RATES ; Dose-Response Relationship, Radiation ; Female ; Femoral arteries ; Femoral Artery - diagnostic imaging ; Femoral Artery - surgery ; Gamma Rays - therapeutic use ; Graft Occlusion, Vascular - epidemiology ; Graft Occlusion, Vascular - etiology ; Graft Occlusion, Vascular - therapy ; Humans ; Male ; Middle Aged ; PATIENTS ; Pilot Projects ; Poland ; Radiography ; RADIOLOGY AND NUCLEAR MEDICINE ; Reoperation ; Restenosis ; Risk Factors ; Stents ; THROMBOSIS ; Thrombosis - epidemiology ; Thrombosis - etiology ; Thrombosis - therapy ; Tibial Arteries - diagnostic imaging ; Tibial Arteries - surgery ; Treatment Outcome ; Vascular brachytherapy</subject><ispartof>Cardiovascular radiation medicine, 2002-01, Vol.3 (1), p.2-6</ispartof><rights>2002 Elsevier Science Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c306t-452e15eea709d8418dc229b54d2cf01e3eb472319978ff4812ed60ac4020d76c3</citedby><cites>FETCH-LOGICAL-c306t-452e15eea709d8418dc229b54d2cf01e3eb472319978ff4812ed60ac4020d76c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12479908$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/20650533$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Walichiewicz, Piotr</creatorcontrib><creatorcontrib>Piecuch, Jerzy</creatorcontrib><creatorcontrib>Bia l ̶ as, Brygida</creatorcontrib><creatorcontrib>Orkisz, Witold</creatorcontrib><creatorcontrib>Fija l ̶ kowski, Marek</creatorcontrib><creatorcontrib>Miszczyk, Leszek</creatorcontrib><title>Vascular brachytherapy after percutaneous transluminal angioplasty of superficial femoral arteries—Polish pilot group</title><title>Cardiovascular radiation medicine</title><addtitle>Cardiovasc Radiat Med</addtitle><description>Purpose: The article presents the results of treatment with vascular brachytherapy (VBT) in superficial femoral arteries. This method aims to minimize frequency of restenosis after percutaneous transluminal angioplasty (PTA).
Method: Treatment was carried out in 20 cases. The patients with severe stenoses or total occlusions verified in angiography were selected. In the group of 19 patients, two were women (the average age of the patients was 58.7 years). VBT was performed immediately after PTA. A 15-Gy dose, with high dose rate, was applied. The dose was calculated based on individually chosen distance from the internal surface of the artery wall, which varied from 2 to 3 mm. The mean observation time after treatment was 8 months. The shortest time was 1 month and the longest 14 months. At the end of the observation time, the control DSA angiography was performed on every patient.
Results: During the first 2 months, in three cases, an acute thrombosis in treated artery was observed. In the third month, one treated artery occluded. In the sixth month of observation, one case of acute thrombosis was observed. The rest of the patients were free of restenoses.
Conclusions: (1) In superficial femoral arteries, a low value of ankle brachial pressure index (ABPI; below 0.4) is very probably responsible for acute thrombosis after PTA with or without stent implantation followed by VBT. (2) Diabetes, rest ischaemia before treatment, poor vessel status confirmed in angiography may also be responsible for acute thrombosis after VBT. (3) Anticoagulants or antiplatelet (ticlipidine) treatment must be ordered for 6 months after VBT in patients with implanted stents.</description><subject>Acute thrombosis</subject><subject>Aged</subject><subject>Angioplasty, Balloon</subject><subject>ANTICOAGULANTS</subject><subject>Arterial Occlusive Diseases - complications</subject><subject>Arterial Occlusive Diseases - epidemiology</subject><subject>Arterial Occlusive Diseases - therapy</subject><subject>ARTERIES</subject><subject>BIOMEDICAL RADIOGRAPHY</subject><subject>Blood Vessel Prosthesis Implantation</subject><subject>BRACHYTHERAPY</subject><subject>DOSE RATES</subject><subject>Dose-Response Relationship, Radiation</subject><subject>Female</subject><subject>Femoral arteries</subject><subject>Femoral Artery - diagnostic imaging</subject><subject>Femoral Artery - surgery</subject><subject>Gamma Rays - therapeutic use</subject><subject>Graft Occlusion, Vascular - epidemiology</subject><subject>Graft Occlusion, Vascular - etiology</subject><subject>Graft Occlusion, Vascular - therapy</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>PATIENTS</subject><subject>Pilot Projects</subject><subject>Poland</subject><subject>Radiography</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Reoperation</subject><subject>Restenosis</subject><subject>Risk Factors</subject><subject>Stents</subject><subject>THROMBOSIS</subject><subject>Thrombosis - epidemiology</subject><subject>Thrombosis - etiology</subject><subject>Thrombosis - therapy</subject><subject>Tibial Arteries - diagnostic imaging</subject><subject>Tibial Arteries - surgery</subject><subject>Treatment Outcome</subject><subject>Vascular brachytherapy</subject><issn>1522-1865</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtOwzAQhr0A0VI4AsgSG1gEbOflrBCqeEmVQOKxtVxn3BqlcWQ7oOw4BCfkJCRtBUtWI3m-f2b8IXREyTklNLt4oiljEeVZekrYGSE04RHfQePf5xHa9_6tb2RFnO-hEWVJXhSEj9HHq_SqraTDcyfVsgtLcLLpsNQBHG7AqTbIGmzrcXCy9lW7MrWssKwXxjaV9KHDVmPf9qg2yvQtDSvrBsT1Iwz478-vR1sZv8SNqWzAC2fb5gDtall5ONzWCXq5uX6e3kWzh9v76dUsUjHJQpSkDGgKIHNSlDyhvFSMFfM0KZnShEIM8yRnMS2KnGudcMqgzIhUCWGkzDMVT9DJZq71wQivTAC1VLauQQXBSJaSNI57Kt1QylnvHWjROLOSrhOUiEGxWCsWg0tBmFgrFrzPHW9yTTtfQfmX2vrtgcsNAP0f3w244QSoFZTGDReU1vyz4gfBcpFR</recordid><startdate>200201</startdate><enddate>200201</enddate><creator>Walichiewicz, Piotr</creator><creator>Piecuch, Jerzy</creator><creator>Bia l ̶ as, Brygida</creator><creator>Orkisz, Witold</creator><creator>Fija l ̶ kowski, Marek</creator><creator>Miszczyk, Leszek</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>200201</creationdate><title>Vascular brachytherapy after percutaneous transluminal angioplasty of superficial femoral arteries—Polish pilot group</title><author>Walichiewicz, Piotr ; Piecuch, Jerzy ; Bia l ̶ as, Brygida ; Orkisz, Witold ; Fija l ̶ kowski, Marek ; Miszczyk, Leszek</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c306t-452e15eea709d8418dc229b54d2cf01e3eb472319978ff4812ed60ac4020d76c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Acute thrombosis</topic><topic>Aged</topic><topic>Angioplasty, Balloon</topic><topic>ANTICOAGULANTS</topic><topic>Arterial Occlusive Diseases - complications</topic><topic>Arterial Occlusive Diseases - epidemiology</topic><topic>Arterial Occlusive Diseases - therapy</topic><topic>ARTERIES</topic><topic>BIOMEDICAL RADIOGRAPHY</topic><topic>Blood Vessel Prosthesis Implantation</topic><topic>BRACHYTHERAPY</topic><topic>DOSE RATES</topic><topic>Dose-Response Relationship, Radiation</topic><topic>Female</topic><topic>Femoral arteries</topic><topic>Femoral Artery - diagnostic imaging</topic><topic>Femoral Artery - surgery</topic><topic>Gamma Rays - therapeutic use</topic><topic>Graft Occlusion, Vascular - epidemiology</topic><topic>Graft Occlusion, Vascular - etiology</topic><topic>Graft Occlusion, Vascular - therapy</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>PATIENTS</topic><topic>Pilot Projects</topic><topic>Poland</topic><topic>Radiography</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Reoperation</topic><topic>Restenosis</topic><topic>Risk Factors</topic><topic>Stents</topic><topic>THROMBOSIS</topic><topic>Thrombosis - epidemiology</topic><topic>Thrombosis - etiology</topic><topic>Thrombosis - therapy</topic><topic>Tibial Arteries - diagnostic imaging</topic><topic>Tibial Arteries - surgery</topic><topic>Treatment Outcome</topic><topic>Vascular brachytherapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Walichiewicz, Piotr</creatorcontrib><creatorcontrib>Piecuch, Jerzy</creatorcontrib><creatorcontrib>Bia l ̶ as, Brygida</creatorcontrib><creatorcontrib>Orkisz, Witold</creatorcontrib><creatorcontrib>Fija l ̶ kowski, Marek</creatorcontrib><creatorcontrib>Miszczyk, Leszek</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>Cardiovascular radiation medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Walichiewicz, Piotr</au><au>Piecuch, Jerzy</au><au>Bia l ̶ as, Brygida</au><au>Orkisz, Witold</au><au>Fija l ̶ kowski, Marek</au><au>Miszczyk, Leszek</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vascular brachytherapy after percutaneous transluminal angioplasty of superficial femoral arteries—Polish pilot group</atitle><jtitle>Cardiovascular radiation medicine</jtitle><addtitle>Cardiovasc Radiat Med</addtitle><date>2002-01</date><risdate>2002</risdate><volume>3</volume><issue>1</issue><spage>2</spage><epage>6</epage><pages>2-6</pages><issn>1522-1865</issn><abstract>Purpose: The article presents the results of treatment with vascular brachytherapy (VBT) in superficial femoral arteries. This method aims to minimize frequency of restenosis after percutaneous transluminal angioplasty (PTA).
Method: Treatment was carried out in 20 cases. The patients with severe stenoses or total occlusions verified in angiography were selected. In the group of 19 patients, two were women (the average age of the patients was 58.7 years). VBT was performed immediately after PTA. A 15-Gy dose, with high dose rate, was applied. The dose was calculated based on individually chosen distance from the internal surface of the artery wall, which varied from 2 to 3 mm. The mean observation time after treatment was 8 months. The shortest time was 1 month and the longest 14 months. At the end of the observation time, the control DSA angiography was performed on every patient.
Results: During the first 2 months, in three cases, an acute thrombosis in treated artery was observed. In the third month, one treated artery occluded. In the sixth month of observation, one case of acute thrombosis was observed. The rest of the patients were free of restenoses.
Conclusions: (1) In superficial femoral arteries, a low value of ankle brachial pressure index (ABPI; below 0.4) is very probably responsible for acute thrombosis after PTA with or without stent implantation followed by VBT. (2) Diabetes, rest ischaemia before treatment, poor vessel status confirmed in angiography may also be responsible for acute thrombosis after VBT. (3) Anticoagulants or antiplatelet (ticlipidine) treatment must be ordered for 6 months after VBT in patients with implanted stents.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>12479908</pmid><doi>10.1016/S1522-1865(02)00148-8</doi><tpages>5</tpages></addata></record> |
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subjects | Acute thrombosis Aged Angioplasty, Balloon ANTICOAGULANTS Arterial Occlusive Diseases - complications Arterial Occlusive Diseases - epidemiology Arterial Occlusive Diseases - therapy ARTERIES BIOMEDICAL RADIOGRAPHY Blood Vessel Prosthesis Implantation BRACHYTHERAPY DOSE RATES Dose-Response Relationship, Radiation Female Femoral arteries Femoral Artery - diagnostic imaging Femoral Artery - surgery Gamma Rays - therapeutic use Graft Occlusion, Vascular - epidemiology Graft Occlusion, Vascular - etiology Graft Occlusion, Vascular - therapy Humans Male Middle Aged PATIENTS Pilot Projects Poland Radiography RADIOLOGY AND NUCLEAR MEDICINE Reoperation Restenosis Risk Factors Stents THROMBOSIS Thrombosis - epidemiology Thrombosis - etiology Thrombosis - therapy Tibial Arteries - diagnostic imaging Tibial Arteries - surgery Treatment Outcome Vascular brachytherapy |
title | Vascular brachytherapy after percutaneous transluminal angioplasty of superficial femoral arteries—Polish pilot group |
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