Anatomy of Protein Electrospray Ionization Mass Spectra by Superconducting Tunnel Junction Mass and Energy Spectrometry

Cryogenic superconducting tunnel junction (STJ) detectors have the advantage of single-particle sensitivity, high quantum efficiency, low noise, and the ability to detect the time and relative impact energy of deposited ions. This makes them attractive for use in mass spectrometry (MS) and as a form...

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Veröffentlicht in:	Analytical chemistry (Washington) 2022-04, Vol.94 (13), p.5284-5292
Hauptverfasser:	Jiang, Li-Xue, Plath, Logan D, Halim, Mohammad A, Friedrich, Stephan, Bier, Mark E
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Animals Bovine serum albumin Carbonic anhydrase Carbonic anhydrases Cattle Chemistry Cytochrome Cytochrome c Cytochromes Electrospraying Energy Fragments Horses IgG antibody Immunoglobulin G Ionization Ions Low noise Mass spectra Mass spectrometers Mass spectrometry Mass spectroscopy Mice Monomers Proteins Quadrupoles Quantum efficiency Scientific imaging Serum albumin Spectrometers Spectrometry, Mass, Electrospray Ionization - methods Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Spectroscopy Spectrum Analysis Superconductivity Tunnel junctions
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