Requirement for theXrcc1DNA Base Excision Repair Gene during Early Mouse Development

Surveillance and repair of DNA damage are essential for maintaining the integrity of the genetic information that is needed for normal development. Several multienzyme pathways, including the excision repair of damaged or missing bases, carry out DNA repair in mammals. We determined the developmenta...

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Veröffentlicht in:	Developmental biology 1999-04, Vol.208 (2), p.513-529
Hauptverfasser:	Tebbs, Robert S., Flannery, Margaret L., Meneses, Juanito J., Hartmann, Andreas, Tucker, James D., Thompson, Larry H., Cleaver, James E., Pedersen, Roger A.
Format:	Artikel
Sprache:	eng
Schlagworte:	base excision repair DNA damage embryonic lethality gene targeting mouse XRCC1
Online-Zugang:	Volltext
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