Protective effect of selenomethionine on intestinal injury induced by T- 2 toxin

T-2 toxin is the most toxic as a type A trichothecenes, which could contaminate grains, especially in wheat and corn. It can cause immune suppression, neurotoxicity, the apoptosis of cells and even induce tumorigenesis. Recent studies have indicated that selenium (Se) have protective effect against...

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Veröffentlicht in:	Research in veterinary science 2020-10, Vol.132 (C), p.439-447
Hauptverfasser:	Liu, Yumei, Yang, Yuxiang, Dong, Ruiqi, Zhang, Zixiang, Jia, Fangfang, Yu, Haotong, Wang, Yuqin, Zhang, Ziqiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Feed - analysis Animals Antioxidants Antioxidants - administration & dosage Antioxidants - pharmacology Apoptosis Cell cycle Diet Diet - veterinary Dietary supplements Dietary Supplements - analysis Dose-Response Relationship, Drug Enzymes Feeds Food contamination & poisoning Gene expression IL-1β Inflammation Inflammatory response Interleukin 6 Intestinal barrier Intestine Jejunal injury Jejunum Jejunum - drug effects Jejunum - pathology Laboratory animals Male Mycotoxins Neurotoxicity Oral administration Oxidative stress Pretreatment Protective Agents - administration & dosage Protective Agents - pharmacology Rabbits Random Allocation Reagents Selenium Selenomethionine Selenomethionine - administration & dosage Selenomethionine - pharmacology T-2 toxin T-2 Toxin - toxicity Toxicity Toxins Trichothecenes Tumor necrosis factor-α Tumorigenesis Veterinary medicine Zonula occludens-1 protein
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