Anticonvulsant drug polytherapy stops status epilepticus and prevents neuronal loss in soman‐exposed rats

Introduction When treatment of status epilepticus (SE) is delayed, seizures become self‐sustaining and refractory to benzodiazepine therapy. Chemical warfare nerve agents (CWNAs), such as soman(GD), increase acetylcholine through inhibition of acetylcholine sterase and can lead to SE if seizures are...

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Veröffentlicht in:The FASEB journal 2018-10, Vol.31 (S1)
Hauptverfasser: Stone, Michael, Schultz, Caroline, Rossetti, Franco, Walker, Katie, Kundrick, Erica, O'Brien, Sean, Marrero‐Rosado, Brenda, Niquet, Jerome, Wasterlain, Claude, Lumley, Lucille A.
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Sprache:eng
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