In vivo melanoma imaging based on dynamic nuclear polarization enhancement in melanin pigment of living mice using in vivo dynamic nuclear polarization magnetic resonance imaging

Melanin is a pigment that includes free radicals and is widely distributed in living animals. Malignant melanoma is one of the most progressive tumors in humans with increasing incidence worldwide, and has shown resistance to chemotherapy, resulting in high mortality at the metastatic stage. In gene...

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Veröffentlicht in:	Free radical biology & medicine 2019-04, Vol.134 (C), p.99-105
Hauptverfasser:	Hyodo, Fuminori, Naganuma, Tatsuya, Eto, Hinako, Murata, Masaharu, Utsumi, Hideo, Matsuo, Masayuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals DNP-MRI Female Free radicals Imaging Magnetic Resonance Imaging - methods Melanin Melanins - metabolism Melanoma Melanoma, Experimental - metabolism Melanoma, Experimental - pathology Mice Mice, Inbred C57BL Nuclear Magnetic Resonance, Biomolecular - methods Signal Processing, Computer-Assisted
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