Myocardial iron homeostasis and hepcidin expression in a rat model of heart failure at different levels of dietary iron intake

Up to 50% of patients with chronic heart failure (HF) have systemic iron deficiency, which contributes to symptoms and poor prognosis. Myocardial iron deficiency (MID) in HF patients has been recently documented, but its causes and consequences are unknown. The goal of our study was to address these...

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Veröffentlicht in:Biochimica et biophysica acta. General subjects 2019-04, Vol.1863 (4), p.703-713
Hauptverfasser: Petrak, Jiri, Havlenova, Tereza, Krijt, Matyas, Behounek, Matej, Franekova, Janka, Cervenka, Ludek, Pluhacek, Tomas, Vyoral, Daniel, Melenovsky, Vojtech
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Sprache:eng
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