The C‐Terminal Domain of α‐Synuclein Confers Steric Stabilization on Synaptic Vesicle‐Like Surfaces

While α‐synuclein, an intrinsically disordered protein linked to Parkinson's disease, has been shown to associate with membrane organelles, its overall cellular function remains nebulous. α‐Synuclein binds to membranes through its amino‐terminal domain (first ≈100 residues), but there is no con...

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Veröffentlicht in:Advanced materials interfaces 2020-07, Vol.7 (14), p.n/a
Hauptverfasser: Chung, Peter J., Hwang, Hyeondo Luke, Slaw, Benjamin R., Leong, Alessandra, Adams, Erin J., Lee, Ka Yee C.
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Sprache:eng
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