l-lysine confers neuroprotection by suppressing inflammatory response via microRNA-575/PTEN signaling after mouse intracerebral hemorrhage injury

l-lysine is a basic amino acid that has been shown to exert neuroprotective effect. However, the underlying mechanism remains to be elucidated. In this study, we investigate how l-lysine exerts its neuroprotective effect in hemin-insulted mouse cortical neurons in vitro and the mouse model of intrac...

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Veröffentlicht in:	Experimental neurology 2020-05, Vol.327 (C), p.113214-113214, Article 113214
Hauptverfasser:	Cheng, Jing, Tang, Jun-Chun, Pan, Meng-Xian, Chen, Song-Feng, Zhao, Dan, Zhang, Ya, Liao, Hua-Bao, Zhuang, Yang, Lei, Rui-Xue, Wang, Shu, Liu, An-Chun, Chen, Juan, Zhang, Zhao-Hui, Li, Huan-Ting, Wan, Qi, Chen, Qian-Xue
Format:	Artikel
Sprache:	eng
Schlagworte:	Inflammatory response Intracerebral hemorrhage l-lysine M2 microglia MicroRNA-575 Neuroprotection PTEN
Online-Zugang:	Volltext
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