Isolation of Tryptanthrin and Reassessment of Evidence for Its Isobaric Isostere Wrightiadione in Plants of the Wrightia Genus

A series of Wrightia hanleyi extracts was screened for activity against Mycobacterium tuberculosis H37Rv. One active fraction contained a compound that initially appeared to be either the isoflavonoid wrightiadione or the alkaloid tryptanthrin, both of which have been previously reported in other Wr...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2019-03, Vol.82 (3), p.440-448
Hauptverfasser:	Garcellano, Rhea C, Moinuddin, Syed G. A, Young, Robert P, Zhou, Mowei, Bowden, Mark E, Renslow, Ryan S, Yesiltepe, Yasemin, Thomas, Dennis G, Colby, Sean M, Chouinard, Christopher D, Nagy, Gabe, Attah, Isaac K, Ibrahim, Yehia M, Ma, Rui, Franzblau, Scott G, Lewis, Norman G, Aguinaldo, Alicia M, Cort, John R
Format:	Artikel
Sprache:	eng
Schlagworte:	NMR, Alkaloid, Flavanoid, SLIM-MS, Plants, Metabolite, Chemical Shift Prediction, Collisional Cross Section
Online-Zugang:	Volltext
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