Phosphonated Calixarene as a “Molecular Glue” for Protein Crystallization

Protein crystallization remains a serious bottleneck to structure determination by X-ray diffraction methods. Compounds acting as “molecular glue” provide a promising strategy to overcome this bottleneck. Such molecules interact via noncovalent bonds with two or more protein surfaces to promote latt...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Crystal growth & design 2018-04, Vol.18 (4), p.2467-2473
Hauptverfasser:	Alex, Jimi M, Rennie, Martin L, Volpi, Stefano, Sansone, Francesco, Casnati, Alessandro, Crowley, Peter B
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!