Synthesis of a suite of click-compatible sugar analogs for probing carbohydrate metabolism

Metabolic labeling based on the click chemistry between alkynyl and azido groups offers a powerful tool to study the function of carbohydrates in living systems, including plants. Herein, we describe the chemical synthesis of six alkynyl-modified sugars designed as analogs to D-glucose, D-mannose, L...

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Veröffentlicht in:	Carbohydrate research 2016-10, Vol.433 (C), p.54-62
Hauptverfasser:	Wang, Bo, McClosky, Daniel D., Anderson, Charles T., Chen, Gong
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbohydrate Metabolism Click Chemistry Deoxyglucose - analogs & derivatives Glucose - analogs & derivatives Labeling probe Mannose - analogs & derivatives Molecular Structure Monosaccharides - chemical synthesis Monosaccharides - chemistry Rhamnose - analogs & derivatives Sucrose - analogs & derivatives Sucrose - chemical synthesis
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