Lipid Cross-Linking of Nanolipoprotein Particles Substantially Enhances Serum Stability and Cellular Uptake

Nanolipoprotein particles (NLPs) consist of a discoidal phospholipid lipid bilayer confined by an apolipoprotein belt. NLPs are a promising platform for a variety of biomedical applications due to their biocompatibility, size, definable composition, and amphipathic characteristics. However, poor ser...

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Veröffentlicht in:	ACS applied materials & interfaces 2016-08, Vol.8 (32), p.20549-20557
Hauptverfasser:	Gilmore, Sean F, Blanchette, Craig D, Scharadin, Tiffany M, Hura, Greg L, Rasley, Amy, Corzett, Michele, Pan, Chong-xian, Fischer, Nicholas O, Henderson, Paul T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals BASIC BIOLOGICAL SCIENCES Cell Line, Tumor Chromatography, Gel cross-linking DiynePC drug delivery Humans Lipid Bilayers Mice nanoparticles Nanoparticles - chemistry NLP Phospholipids rHDL serum stability
Online-Zugang:	Volltext
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