On the predictability of the orientation of protein domains joined by a spanning alpha-helical linker

Connecting proteins together in prescribed geometric arrangements is an important element in new areas of biomolecular design. In this study, we characterize the degree of three-dimensional orientational control that can be achieved when two protein domains that have alpha-helical termini are joined...

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Veröffentlicht in:	Protein engineering, design and selection design and selection, 2015-11, Vol.28 (11), p.491-500
Hauptverfasser:	Lai, Yen-Ting, Jiang, Lin, Chen, Wuyang, Yeates, Todd O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Models, Molecular Molecular Sequence Data Pliability Protein Engineering Protein Structure, Secondary Protein Structure, Tertiary Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - metabolism Sequence Alignment Synthetic Biology
Online-Zugang:	Volltext
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