Rediscovery by Whole Genome Sequencing: Classical Mutations and Genome Polymorphisms in Neurospora crassa

Classical forward genetics has been foundational to modern biology, and has been the paradigm for characterizing the role of genes in shaping phenotypes for decades. In recent years, reverse genetics has been used to identify the functions of genes, via the intentional introduction of variation and...

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Veröffentlicht in:	G3 : genes - genomes - genetics 2011-06, Vol.1 (4)
Hauptverfasser:	McCluskey, Kevin, Wiest, Aric E., Grigoriev, Igor V., Lipzen, Anna, Martin, Joel, Schackwitz, Wendy, Baker, Scott E.
Format:	Artikel
Sprache:	eng
Schlagworte:	BASIC BIOLOGICAL SCIENCES single nucleotide polymorphism, SNP, indel, comparative genomics, classical mutant
Online-Zugang:	Volltext
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