Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals

In bilaterian animals, such as humans, flies and worms, hundreds of microRNAs (miRNAs), some conserved throughout bilaterian evolution, collectively regulate a substantial fraction of the transcriptome. In addition to miRNAs, other bilaterian small RNAs, known as Piwi-interacting RNAs (piRNAs), prot...

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Veröffentlicht in:	Nature 2008-10, Vol.455 (7217), p.1193-1197
Hauptverfasser:	Grimson, Andrew, Srivastava, Mansi, Fahey, Bryony, Woodcroft, Ben J., Chiang, H. Rosaria, King, Nicole, Degnan, Bernard M., Rokhsar, Daniel S., Bartel, David P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphimedon Animals Base Sequence Bilateria Biological and medical sciences Biological evolution Eukaryotic Cells - metabolism Evolution Evolution, Molecular Fundamental and applied biological sciences. Psychology Gene Expression Regulation Genetics of eukaryotes. Biological and molecular evolution Humanities and Social Sciences Humans Life sciences MicroRNAs - genetics multidisciplinary Nematostella vectensis Phylogeny Ribonucleic acid RNA RNA, Small Interfering - genetics Science Science (multidisciplinary) Sea Anemones - genetics Sequence Analysis
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