Synthetic biology and the development of tools for metabolic engineering
Synthetic biology can significantly advance metabolic engineering by contributing tools (minimal hosts, vectors, genetic controllers, characterized enzymes). The development of these tools significantly reduced the costs and time to develop the antimalarial drug artemisinin, but the availability of...
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| Veröffentlicht in: | Metabolic engineering 2012-05, Vol.14 (3), p.189-195 |
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| container_end_page | 195 |
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| container_issue | 3 |
| container_start_page | 189 |
| container_title | Metabolic engineering |
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| creator | Keasling, Jay D. |
| description | Synthetic biology can significantly advance metabolic engineering by contributing tools (minimal hosts, vectors, genetic controllers, characterized enzymes). The development of these tools significantly reduced the costs and time to develop the antimalarial drug artemisinin, but the availability of more tools could have reduced these costs substantially. |
| doi_str_mv | 10.1016/j.ymben.2012.01.004 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1096-7176 |
| ispartof | Metabolic engineering, 2012-05, Vol.14 (3), p.189-195 |
| issn | 1096-7176 1096-7184 |
| language | eng |
| recordid | cdi_osti_scitechconnect_1153277 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Antimalarials - chemical synthesis Antimalarials - economics Antimalarials - metabolism Artemisinin Artemisinins - chemical synthesis Artemisinins - economics Artemisinins - metabolism Drug Design Engineering Enzymes Genetic Hosts Lactones - chemical synthesis Lactones - economics Lactones - metabolism Metabolic Metabolic Engineering - economics Metabolic Engineering - methods Metabolic Engineering - trends Synthetic Biology - economics Synthetic Biology - methods Synthetic Biology - trends |
| title | Synthetic biology and the development of tools for metabolic engineering |
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