Transcriptional burst frequency and burst size are equally modulated across the human genome

Gene expression occurs either as an episodic process, characterized by pulsatile bursts, or as a constitutive process, characterized by a Poisson-like accumulation of gene products. It is not clear which mode of gene expression (constitutive versus bursty) predominates across a genome or how transcr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2012-10, Vol.109 (43), p.17454-17459
Hauptverfasser:	Dar, Roy D, Razooky, Brandon S, Singh, Abhyudai, Trimeloni, Thomas V, McCollum, James M, Cox, Chris D, Simpson, Michael L, Weinberger, Leor S
Format:	Artikel
Sprache:	eng
Schlagworte:	Autocorrelation Biological Sciences Chromosomes Fluorescence fluorescence microscopy Gene Expression Genes Genetic loci Genetic Vectors Genome, Human Genomics HIV 1 Human genome Humans Hydroxamic Acids - pharmacology Lentivirus - genetics loci Microscopy, Fluorescence noise biology Noise measurement promoter regions Promoter Regions, Genetic quantitative analysis T lymphocytes Trajectories transactivators transcription (genetics) Transcription, Genetic - drug effects tumor necrosis factor-alpha Tumor Necrosis Factor-alpha - pharmacology Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!