Doubling the Size of the Glucocorticoid Receptor Ligand Binding Pocket by Deacylcortivazol
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| Veröffentlicht in: | Molecular and Cellular Biology 2008-03, Vol.28 (6), p.1915-1923 |
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| container_title | Molecular and Cellular Biology |
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| creator | Suino-Powell, Kelly Xu, Yong Zhang, Chenghai Tao, Yong-guang Tolbert, W. David Simons, S. Stoney Xu, H. Eric |
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| doi_str_mv | 10.1128/MCB.01541-07 |
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</description><identifier>ISSN: 0270-7306</identifier><identifier>ISSN: 1098-5549</identifier><identifier>EISSN: 1098-5549</identifier><identifier>DOI: 10.1128/MCB.01541-07</identifier><identifier>PMID: 18160712</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>Amino Acid Motifs ; Amino Acid Sequence ; Binding Sites - drug effects ; CRYSTAL STRUCTURE ; Crystallography, X-Ray ; Drug Design ; DRUGS ; EXPANSION ; GESELLSCHAFT FUER ANLAGEN- UND REAKTORSICHERHEIT ; GLUCOCORTICOIDS ; Herpes Simplex Virus Protein Vmw65 - genetics ; Herpes Simplex Virus Protein Vmw65 - physiology ; Histone Acetyltransferases - chemistry ; Histone Acetyltransferases - metabolism ; Humans ; INTERACTIONS ; LIGANDS ; MATERIALS SCIENCE ; Models, Molecular ; Molecular Sequence Data ; NESTS ; Nuclear Receptor Coactivator 1 ; Nuclear Receptor Coactivator 2 - chemistry ; Nuclear Receptor Coactivator 2 - metabolism ; Nuclear Receptor Coactivator 3 ; Nuclear Receptor Coactivators ; Oncogene Proteins - chemistry ; Oncogene Proteins - metabolism ; Peptide Fragments - chemistry ; Peptide Fragments - drug effects ; Pregnatrienes - pharmacology ; Protein Binding ; Protein Conformation - drug effects ; RECEPTORS ; Receptors, Glucocorticoid - chemistry ; Receptors, Glucocorticoid - drug effects ; Recombinant Fusion Proteins - chemistry ; Recombinant Fusion Proteins - drug effects ; Recombinant Fusion Proteins - physiology ; SIZE ; SPACE ; STEROID HORMONES ; STEROIDS ; Trans-Activators - chemistry ; Trans-Activators - metabolism ; TRANSCRIPTION FACTORS ; Transcription Factors - chemistry ; Transcription Factors - metabolism</subject><ispartof>Molecular and Cellular Biology, 2008-03, Vol.28 (6), p.1915-1923</ispartof><rights>Copyright © 2008, American Society for Microbiology 2008</rights><rights>Copyright © 2008, American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c623t-701fa5264e92d3d9aa613b511a7f59c654276062f042067e1b2cc7417527c3573</citedby><cites>FETCH-LOGICAL-c623t-701fa5264e92d3d9aa613b511a7f59c654276062f042067e1b2cc7417527c3573</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268401/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268401/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18160712$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/1006525$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Suino-Powell, Kelly</creatorcontrib><creatorcontrib>Xu, Yong</creatorcontrib><creatorcontrib>Zhang, Chenghai</creatorcontrib><creatorcontrib>Tao, Yong-guang</creatorcontrib><creatorcontrib>Tolbert, W. David</creatorcontrib><creatorcontrib>Simons, S. Stoney</creatorcontrib><creatorcontrib>Xu, H. Eric</creatorcontrib><creatorcontrib>Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)</creatorcontrib><title>Doubling the Size of the Glucocorticoid Receptor Ligand Binding Pocket by Deacylcortivazol</title><title>Molecular and Cellular Biology</title><addtitle>Mol Cell Biol</addtitle><description>Article Usage Stats
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</description><subject>Amino Acid Motifs</subject><subject>Amino Acid Sequence</subject><subject>Binding Sites - drug effects</subject><subject>CRYSTAL STRUCTURE</subject><subject>Crystallography, X-Ray</subject><subject>Drug Design</subject><subject>DRUGS</subject><subject>EXPANSION</subject><subject>GESELLSCHAFT FUER ANLAGEN- UND REAKTORSICHERHEIT</subject><subject>GLUCOCORTICOIDS</subject><subject>Herpes Simplex Virus Protein Vmw65 - genetics</subject><subject>Herpes Simplex Virus Protein Vmw65 - physiology</subject><subject>Histone Acetyltransferases - chemistry</subject><subject>Histone Acetyltransferases - metabolism</subject><subject>Humans</subject><subject>INTERACTIONS</subject><subject>LIGANDS</subject><subject>MATERIALS SCIENCE</subject><subject>Models, Molecular</subject><subject>Molecular Sequence Data</subject><subject>NESTS</subject><subject>Nuclear Receptor Coactivator 1</subject><subject>Nuclear Receptor Coactivator 2 - chemistry</subject><subject>Nuclear Receptor Coactivator 2 - metabolism</subject><subject>Nuclear Receptor Coactivator 3</subject><subject>Nuclear Receptor Coactivators</subject><subject>Oncogene Proteins - chemistry</subject><subject>Oncogene Proteins - metabolism</subject><subject>Peptide Fragments - chemistry</subject><subject>Peptide Fragments - drug effects</subject><subject>Pregnatrienes - pharmacology</subject><subject>Protein Binding</subject><subject>Protein Conformation - drug effects</subject><subject>RECEPTORS</subject><subject>Receptors, Glucocorticoid - chemistry</subject><subject>Receptors, Glucocorticoid - drug effects</subject><subject>Recombinant Fusion Proteins - chemistry</subject><subject>Recombinant Fusion Proteins - drug effects</subject><subject>Recombinant Fusion Proteins - physiology</subject><subject>SIZE</subject><subject>SPACE</subject><subject>STEROID HORMONES</subject><subject>STEROIDS</subject><subject>Trans-Activators - chemistry</subject><subject>Trans-Activators - metabolism</subject><subject>TRANSCRIPTION FACTORS</subject><subject>Transcription Factors - chemistry</subject><subject>Transcription Factors - metabolism</subject><issn>0270-7306</issn><issn>1098-5549</issn><issn>1098-5549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kUtv1DAUhS0EokNhxxoFFqxI8SO2J5tKdAoFaRCIx4aN5dw4E4NjD7bTavrryUxGPBasfCV_59yjexB6TPAZIXT58v3q4gwTXpESyztoQXC9LDmv6rtoganEpWRYnKAHKX3HGIsas_vohCyJwJLQBfp2GcbGWb8pcm-Kz_bWFKE7zFduhAAhZgvBtsUnA2abQyzWdqN9W1xY3-5lHwP8MLlodsWl0bBzB8W1vg3uIbrXaZfMo-N7ir6-ef1l9bZcf7h6t3q1LkFQlkuJSac5FZWpacvaWmtBWMMJ0bLjNQheUSmwoB2uKBbSkIYCyIpITiUwLtkpOp99t2MzmBaMz1E7tY120HGngrbq3x9ve7UJ14pSsawwmQyezQYhZasS2Gygh-C9gazIdDRO-QQ9P26J4edoUlaDTWCc096EMSmKlxUXTEzgixmEGFKKpvudhGC1b0xNjalDYwrv0z_5O_0f-FjRBMgZsL4LcdA3IbpWZb1zIXZRe7BJsf9YP52Vvd30NzYapdOgBmjURApFasLZL-fMrf8</recordid><startdate>20080301</startdate><enddate>20080301</enddate><creator>Suino-Powell, Kelly</creator><creator>Xu, Yong</creator><creator>Zhang, Chenghai</creator><creator>Tao, Yong-guang</creator><creator>Tolbert, W. 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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>18160712</pmid><doi>10.1128/MCB.01541-07</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0270-7306 |
| ispartof | Molecular and Cellular Biology, 2008-03, Vol.28 (6), p.1915-1923 |
| issn | 0270-7306 1098-5549 1098-5549 |
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| recordid | cdi_osti_scitechconnect_1006525 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Amino Acid Motifs Amino Acid Sequence Binding Sites - drug effects CRYSTAL STRUCTURE Crystallography, X-Ray Drug Design DRUGS EXPANSION GESELLSCHAFT FUER ANLAGEN- UND REAKTORSICHERHEIT GLUCOCORTICOIDS Herpes Simplex Virus Protein Vmw65 - genetics Herpes Simplex Virus Protein Vmw65 - physiology Histone Acetyltransferases - chemistry Histone Acetyltransferases - metabolism Humans INTERACTIONS LIGANDS MATERIALS SCIENCE Models, Molecular Molecular Sequence Data NESTS Nuclear Receptor Coactivator 1 Nuclear Receptor Coactivator 2 - chemistry Nuclear Receptor Coactivator 2 - metabolism Nuclear Receptor Coactivator 3 Nuclear Receptor Coactivators Oncogene Proteins - chemistry Oncogene Proteins - metabolism Peptide Fragments - chemistry Peptide Fragments - drug effects Pregnatrienes - pharmacology Protein Binding Protein Conformation - drug effects RECEPTORS Receptors, Glucocorticoid - chemistry Receptors, Glucocorticoid - drug effects Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - drug effects Recombinant Fusion Proteins - physiology SIZE SPACE STEROID HORMONES STEROIDS Trans-Activators - chemistry Trans-Activators - metabolism TRANSCRIPTION FACTORS Transcription Factors - chemistry Transcription Factors - metabolism |
| title | Doubling the Size of the Glucocorticoid Receptor Ligand Binding Pocket by Deacylcortivazol |
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