The Crystal Structure of Bacteriophage HK97 gp6: Defining a Large Family of Head–Tail Connector Proteins

The final step in the morphogenesis of long-tailed double-stranded DNA bacteriophages is the joining of the DNA-filled head to the tail. The connector is a specialized structure of the head that serves as the interface for tail attachment and the point of egress for DNA from the head during infectio...

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Veröffentlicht in:	Journal of molecular biology 2010-01, Vol.395 (4), p.754-768
Hauptverfasser:	Cardarelli, Lia, Lam, Robert, Tuite, Ashleigh, Baker, Lindsay A., Sadowski, Paul D., Radford, Devon R., Rubinstein, John L., Battaile, Kevin P., Chirgadze, Nickolay, Maxwell, Karen L., Davidson, Alan R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacteria bacteriophage assembly BACTERIOPHAGES CONNECTORS CRYSTAL STRUCTURE Crystallography, X-Ray DIMENSIONS DNA FUNCTIONALS head–tail connector HK97 MATERIALS SCIENCE MICROSCOPY Microscopy, Electron, Transmission Models, Molecular Molecular Sequence Data MORPHOGENESIS Mutagenesis Phage HK97 Phage SPP1 Protein Multimerization Protein Structure, Quaternary Protein Subunits PROTEINS Recombinant Proteins - chemistry Recombinant Proteins - genetics Recombinant Proteins - ultrastructure Sequence Homology, Amino Acid SIMULATION Siphoviridae - chemistry Siphoviridae - genetics Siphoviridae - physiology Siphoviridae - ultrastructure Static Electricity Structural Homology, Protein SYMMETRY Viral Proteins - chemistry Viral Proteins - genetics Viral Proteins - physiology Viral Proteins - ultrastructure Virus Assembly X-ray crystallography
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