난독증 아동의 뇌백질 연결성 변화 : 환자-대조군 연구

Objectives To compare the white matter microstructure of dyslexic children with normal children using diffusion tensor imaging. Methods Twenty one dyslexic children and 24 normal control children were recruited in the second and third grade of elementary school students. The fractional anisotropy (FA) values of 20 representative white matter tracts were estimated from the diffusion tensor imaging data of each subject using the Johns Hopkins University–white matter tractography atlas to determine the difference in white matter integrity between the dyslexic children and normal children. Results Compared to the normal control group, the FA values of the left inferior longitudinal fasciculus [F(1,39)=5.908, p