Synthesis and preliminary in vitro biological activity of non-steroidal cytotoxic estrogens designed for the treatment of breast cancer

The development of resistance to endocrine therapy as well as chemotherapy is presently a major problem in the treatment of breast cancer. To minimize this obstacle, new, more selective and potent, chemotherapeutic agents should be designed. One way to improve selectivity is to link a cytotoxic moie...

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Veröffentlicht in:	Canadian journal of chemistry 1993-09, Vol.71 (9), p.1327-1333
Hauptverfasser:	Bérubé, G, Wheeler, P, Ford, C.H.J, Gallant, M, Tsaltas, Z
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Coordination compounds Exact sciences and technology Inorganic chemistry and origins of life Preparations and properties
Online-Zugang:	Volltext
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