Reversal of pathological pain through specific spinal GABA A receptor subtypes

Inflammatory diseases and neuropathic insults are frequently accompanied by severe and debilitating pain, which can become chronic and often unresponsive to conventional analgesic treatment. A loss of synaptic inhibition in the spinal dorsal horn is considered to contribute significantly to this pai...

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Veröffentlicht in:Nature (London) 2008-01, Vol.451 (7176), p.330-334
Hauptverfasser: Ahmadi, Seifollah, Zeilhofer, Hanns Ulrich, Fritschy, Jean-Marc, Sergejeva, Marina, Reinold, Heiko, Brockhaus, Johannes, Möhler, Hanns, Knabl, Julia, Brune, Kay, Rudolph, Uwe, Witschi, Robert, Hösl, Katharina, Zeilhofer, Ulrike B, Hess, Andreas
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Sprache:eng
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