Short-term pulmonary and systemic effects of hydrocortisone initiated 7-14 days after birth in ventilated very preterm infants: a secondary analysis of a randomised controlled trial

Objective Observational studies in preterm infants suggest that systemic hydrocortisone improves pulmonary condition but may also lead to systemic adverse effects. We report the short-term pulmonary and systemic effects of hydrocortisone initiated in the second week.Design Randomised placebo-control...

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Veröffentlicht in:Archives of Disease in Childhood. Fetal and Neonatal Edition 2022-05, Vol.108 (1), p.F20-F25
Hauptverfasser: Halbmeijer, N.M., Onland, W., Cools, F., Kroon, A., Heide-jalving, M. van der, Dijk, P., Straaten, H.L.M. van, Pas, A.B. te, Mohns, T., Bruneel, E., Heijst, A.F.J. van, Kramer, B., Debeer, A., Zonnenberg, I.A., Marechal, Y., Blom, H., Plaskie, K., Merkus, M.P., Offringa, M., Kaam, A.H. van
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Sprache:eng
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Zusammenfassung:Objective Observational studies in preterm infants suggest that systemic hydrocortisone improves pulmonary condition but may also lead to systemic adverse effects. We report the short-term pulmonary and systemic effects of hydrocortisone initiated in the second week.Design Randomised placebo-controlled trial.Setting Dutch and Belgian neonatal intensive care units.Patients Infants born
DOI:10.1136/archdischild-2022-323882