Biomonitoring of exposure to environmental pollutants in newborns and their parents in Madrid, Spain (BioMadrid): study design and field work results
Abstract In Spain environmental surveillance has mainly relied on measures of selected pollutants in air, water, food and soil. A study was conducted in Madrid to assess the feasibility of implementing a surveillance system of exposure among the general population to specific environmental pollutant...
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Veröffentlicht in: | Gaceta sanitaria 2008-09, Vol.22 (5), p.483-491 |
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creator | Aragonés, Nuria Pérez-Gómez, Beatriz Astray, Jenaro Gil, Elisa María Pérez-Meixeira, Ana De Paz, Concha Iriso, Andrés Cisneros, Margot de Santos, Amparo Arias, Pedro Carlos Sanz, Juan Asensio, Ángel Antonio Fernández, Mario José González, María de León, América Miguel García-Sagredo, José Pollán, Marina López-Abente, Gonzalo Frutos García, José Martínez, Mercedes |
description | Abstract In Spain environmental surveillance has mainly relied on measures of selected pollutants in air, water, food and soil. A study was conducted in Madrid to assess the feasibility of implementing a surveillance system of exposure among the general population to specific environmental pollutants, using biomarkers. The project was basically focused on the environment surrounding newborns. Hence, the study population was made up of 145 triplets of pregnant women at around 8 months’ gestation, their partners, and newborns from two areas, representing the two main types of urban environments in the region, i.e., the City of Madrid and its outlying metropolitan belt. Multiple biologic substrates were collected from each participant in order to assess the most suitable samples for an environmental surveillance system. The selected contaminants represent the main agents to which a population like that of Madrid is exposed every day, including certain heavy metals, persistent organic pollutants and polycyclic aromatic hydrocarbons, as well as micronuclei in peripheral blood, a commonly used unspecific index of cytogenetic damage. In addition, passive air samplers were placed around subjects’ place of residence. This paper reports in detail on the design and response rates, summarizes field work results, and discusses some lessons learned. |
doi_str_mv | 10.1157/13126931 |
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A study was conducted in Madrid to assess the feasibility of implementing a surveillance system of exposure among the general population to specific environmental pollutants, using biomarkers. The project was basically focused on the environment surrounding newborns. Hence, the study population was made up of 145 triplets of pregnant women at around 8 months’ gestation, their partners, and newborns from two areas, representing the two main types of urban environments in the region, i.e., the City of Madrid and its outlying metropolitan belt. Multiple biologic substrates were collected from each participant in order to assess the most suitable samples for an environmental surveillance system. The selected contaminants represent the main agents to which a population like that of Madrid is exposed every day, including certain heavy metals, persistent organic pollutants and polycyclic aromatic hydrocarbons, as well as micronuclei in peripheral blood, a commonly used unspecific index of cytogenetic damage. In addition, passive air samplers were placed around subjects’ place of residence. This paper reports in detail on the design and response rates, summarizes field work results, and discusses some lessons learned.</description><identifier>ISSN: 0213-9111</identifier><identifier>DOI: 10.1157/13126931</identifier><identifier>PMID: 19000531</identifier><language>eng ; spa</language><publisher>Spain: Doyma</publisher><subject>Adolescent ; Adult ; Adults ; Biomarkers ; Child ; Childhood ; Cohort Studies ; Environmental biomonitoring ; Environmental Exposure ; Environmental Monitoring - methods ; Environmental Pollutants - analysis ; Exposure assessment ; Feasibility Studies ; Female ; Humans ; Infant ; Infant, Newborn ; Internal Medicine ; Male ; Micronucleus Tests ; Middle Aged ; Parents ; Pilot Projects ; Pregnancy ; Public Health ; Socioeconomic Factors ; Spain ; Study design ; Surveys and Questionnaires ; Urban Population</subject><ispartof>Gaceta sanitaria, 2008-09, Vol.22 (5), p.483-491</ispartof><rights>Sociedad Española de Salud Pública y Administración Sanitaria</rights><rights>free</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c406t-226cda12302b35dbe1ea1957fa10006fefd387b4cff333e4e0a196238ef1f7583</citedby><cites>FETCH-LOGICAL-c406t-226cda12302b35dbe1ea1957fa10006fefd387b4cff333e4e0a196238ef1f7583</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,315,781,785,865,886,887,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19000531$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aragonés, Nuria</creatorcontrib><creatorcontrib>Pérez-Gómez, Beatriz</creatorcontrib><creatorcontrib>Astray, Jenaro</creatorcontrib><creatorcontrib>Gil, Elisa</creatorcontrib><creatorcontrib>María Pérez-Meixeira, Ana</creatorcontrib><creatorcontrib>De Paz, Concha</creatorcontrib><creatorcontrib>Iriso, Andrés</creatorcontrib><creatorcontrib>Cisneros, Margot</creatorcontrib><creatorcontrib>de Santos, Amparo</creatorcontrib><creatorcontrib>Arias, Pedro</creatorcontrib><creatorcontrib>Carlos Sanz, Juan</creatorcontrib><creatorcontrib>Asensio, Ángel</creatorcontrib><creatorcontrib>Antonio Fernández, Mario</creatorcontrib><creatorcontrib>José González, María</creatorcontrib><creatorcontrib>de León, América</creatorcontrib><creatorcontrib>Miguel García-Sagredo, José</creatorcontrib><creatorcontrib>Pollán, Marina</creatorcontrib><creatorcontrib>López-Abente, Gonzalo</creatorcontrib><creatorcontrib>Frutos García, José</creatorcontrib><creatorcontrib>Martínez, Mercedes</creatorcontrib><title>Biomonitoring of exposure to environmental pollutants in newborns and their parents in Madrid, Spain (BioMadrid): study design and field work results</title><title>Gaceta sanitaria</title><addtitle>Gac Sanit</addtitle><description>Abstract In Spain environmental surveillance has mainly relied on measures of selected pollutants in air, water, food and soil. A study was conducted in Madrid to assess the feasibility of implementing a surveillance system of exposure among the general population to specific environmental pollutants, using biomarkers. The project was basically focused on the environment surrounding newborns. Hence, the study population was made up of 145 triplets of pregnant women at around 8 months’ gestation, their partners, and newborns from two areas, representing the two main types of urban environments in the region, i.e., the City of Madrid and its outlying metropolitan belt. Multiple biologic substrates were collected from each participant in order to assess the most suitable samples for an environmental surveillance system. The selected contaminants represent the main agents to which a population like that of Madrid is exposed every day, including certain heavy metals, persistent organic pollutants and polycyclic aromatic hydrocarbons, as well as micronuclei in peripheral blood, a commonly used unspecific index of cytogenetic damage. In addition, passive air samplers were placed around subjects’ place of residence. This paper reports in detail on the design and response rates, summarizes field work results, and discusses some lessons learned.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Adults</subject><subject>Biomarkers</subject><subject>Child</subject><subject>Childhood</subject><subject>Cohort Studies</subject><subject>Environmental biomonitoring</subject><subject>Environmental Exposure</subject><subject>Environmental Monitoring - methods</subject><subject>Environmental Pollutants - analysis</subject><subject>Exposure assessment</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Micronucleus Tests</subject><subject>Middle Aged</subject><subject>Parents</subject><subject>Pilot Projects</subject><subject>Pregnancy</subject><subject>Public Health</subject><subject>Socioeconomic Factors</subject><subject>Spain</subject><subject>Study design</subject><subject>Surveys and Questionnaires</subject><subject>Urban Population</subject><issn>0213-9111</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkd1OXSEQhbmwqdaa9AkMlzb2tAzs316YWNO_xMYL9ZqwN4NFObADbPU8SN-3nO7T9mrCrA-GtYaQN8DeA9TtBxDAm17AHjlgHMSqB4B98iqle8Y46zv2kuxDzxirBRyQX59sWAdvc4jW39FgKD5PIc0RaQ4U_aONwa_RZ-XoFJybs_I5Ueupx6chRJ-o8prmn2gjnVTEnfpD6Wj1O3o9qXI6KVOWztuPNOVZb6jGZO_8n8vGotP0KcQHGjHNLqfX5IVRLuHRrh6S2y-fby6-rS6vvn6_OL9cjRVr8orzZtQKuGB8ELUeEFBBX7dGQfHXGDRadO1QjcYIIbBCVuSGiw4NmLbuxCE5Xd51KltvvcZnOUW7VnEjg7Iy4hiilpXomWCFPlnoMYaUIpp_LDC5zV7-zb6gxws6zcMa9X9wF3wBzhYAi71Hi1GOrvxgVO4BN5juwxx9cS5BJi6ZvN6ucrtJ1rW84nUrfgPQ-5gI</recordid><startdate>20080901</startdate><enddate>20080901</enddate><creator>Aragonés, Nuria</creator><creator>Pérez-Gómez, Beatriz</creator><creator>Astray, Jenaro</creator><creator>Gil, Elisa</creator><creator>María Pérez-Meixeira, Ana</creator><creator>De Paz, Concha</creator><creator>Iriso, Andrés</creator><creator>Cisneros, Margot</creator><creator>de Santos, Amparo</creator><creator>Arias, Pedro</creator><creator>Carlos Sanz, Juan</creator><creator>Asensio, Ángel</creator><creator>Antonio Fernández, Mario</creator><creator>José González, María</creator><creator>de León, América</creator><creator>Miguel García-Sagredo, José</creator><creator>Pollán, Marina</creator><creator>López-Abente, Gonzalo</creator><creator>Frutos García, José</creator><creator>Martínez, Mercedes</creator><general>Doyma</general><general>Sociedad Española de Salud Pública y Administración Sanitaria, SESPAS</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>77F</scope></search><sort><creationdate>20080901</creationdate><title>Biomonitoring of exposure to environmental pollutants in newborns and their parents in Madrid, Spain (BioMadrid): study design and field work results</title><author>Aragonés, Nuria ; 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A study was conducted in Madrid to assess the feasibility of implementing a surveillance system of exposure among the general population to specific environmental pollutants, using biomarkers. The project was basically focused on the environment surrounding newborns. Hence, the study population was made up of 145 triplets of pregnant women at around 8 months’ gestation, their partners, and newborns from two areas, representing the two main types of urban environments in the region, i.e., the City of Madrid and its outlying metropolitan belt. Multiple biologic substrates were collected from each participant in order to assess the most suitable samples for an environmental surveillance system. 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subjects | Adolescent Adult Adults Biomarkers Child Childhood Cohort Studies Environmental biomonitoring Environmental Exposure Environmental Monitoring - methods Environmental Pollutants - analysis Exposure assessment Feasibility Studies Female Humans Infant Infant, Newborn Internal Medicine Male Micronucleus Tests Middle Aged Parents Pilot Projects Pregnancy Public Health Socioeconomic Factors Spain Study design Surveys and Questionnaires Urban Population |
title | Biomonitoring of exposure to environmental pollutants in newborns and their parents in Madrid, Spain (BioMadrid): study design and field work results |
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