Moving the pH Gate of the Kir1.1 Inward Rectifier Channel

Both structural and functional studies suggest that pH gating of the inward rectifier potassium (K) channel, Kir1.1 (ROMK), is mediated by the convergence of 4 hydrophobic leucines (one from each subunit) near the cytoplasmic bundle-crossing of the inner transmembrane helices. We tested this hypothe...

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Veröffentlicht in:	Channels (Austin, Tex.) Tex.), 2007-01, Vol.1 (1), p.22-29
Hauptverfasser:	Nanazashvili, Mikheil, Li, Hui, Palmer, Lawrence G., Walters, D. Eric, Sackin, Henry
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Biology Bioscience Calcium Cancer Cell Cycle Landes Organogenesis Proteins
Online-Zugang:	Volltext
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