Emerging role of ILK and ELMO2 in the integration of adhesion and migration pathways

Integrins and their associated proteins are essential components of the cellular machinery that modulates adhesion and migration. In particular, integrin-linked kinase (ILK), which binds to the cytoplasmic tail of β1 integrins, is required for migration in a variety of cell types. We previously iden...

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Veröffentlicht in:	Cell adhesion & migration 2012-05, Vol.6 (3), p.168-172
Hauptverfasser:	Ho, Ernest, Dagnino, Lina
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - physiology Binding Biology Bioscience Calcium Cancer Cell Cell Adhesion cell migration Cell Movement Cells, Cultured Cycle Cytoskeletal Proteins - physiology ELMO2 epidermal growth factor Epidermal Growth Factor - physiology Humans ILK integrin-linked kinase integrins keratinocyte Keratinocytes - metabolism Keratinocytes - physiology Landes Organogenesis Protein-Serine-Threonine Kinases - physiology Proteins Rho GTPases Signal Transduction
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