Pancreas Development and Cancer: Wnt/β-Catenin at Issue
β-catenin and Adenomatous poliposis coli (APC) have been implicated in non-ductal pancreatic cancers. As for many other organs, several recent publications show that β-catenin and more largely the Wnt pathway appear to function at the level of pancreatic progenitors and endocrine cells during organo...
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| Veröffentlicht in: | Cell cycle (Georgetown, Tex.) Tex.), 2006-01, Vol.5 (1), p.7-10 |
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| creator | Dessimoz, Jessica Grapin-Botton, Anne |
| description | β-catenin and Adenomatous poliposis coli (APC) have been implicated in non-ductal pancreatic cancers. As for many other organs, several recent publications show that β-catenin and more largely the Wnt pathway appear to function at the level of pancreatic progenitors and endocrine cells during organogenesis. This raises the question of the cell type in which β-catenin is mutated during tumor formation in acinar cell carcinomas, pancreatoblastomas and solid cystic papillary tumors of the pancreas. |
| doi_str_mv | 10.4161/cc.5.1.2293 |
| format | Article |
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This raises the question of the cell type in which β-catenin is mutated during tumor formation in acinar cell carcinomas, pancreatoblastomas and solid cystic papillary tumors of the pancreas.</description><identifier>ISSN: 1538-4101</identifier><identifier>EISSN: 1551-4005</identifier><identifier>DOI: 10.4161/cc.5.1.2293</identifier><identifier>PMID: 16322692</identifier><language>eng</language><publisher>United States: Taylor & Francis</publisher><subject>Animals ; beta Catenin - metabolism ; Binding ; Biology ; Bioscience ; Calcium ; Cancer ; Cell ; Cycle ; Gene Expression Regulation, Developmental ; Gene Expression Regulation, Neoplastic ; Humans ; Landes ; Organogenesis ; Pancreas - embryology ; Pancreatic Neoplasms - metabolism ; Pancreatic Neoplasms - pathology ; Proteins ; Wnt Proteins - metabolism</subject><ispartof>Cell cycle (Georgetown, Tex.), 2006-01, Vol.5 (1), p.7-10</ispartof><rights>Copyright © 2005 Landes Bioscience 2005</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c411t-76113ea007520a0403134e46dff9091fc63407a6d0cdaf5d18771a8ec7858d3e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16322692$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dessimoz, Jessica</creatorcontrib><creatorcontrib>Grapin-Botton, Anne</creatorcontrib><title>Pancreas Development and Cancer: Wnt/β-Catenin at Issue</title><title>Cell cycle (Georgetown, Tex.)</title><addtitle>Cell Cycle</addtitle><description>β-catenin and Adenomatous poliposis coli (APC) have been implicated in non-ductal pancreatic cancers. 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This raises the question of the cell type in which β-catenin is mutated during tumor formation in acinar cell carcinomas, pancreatoblastomas and solid cystic papillary tumors of the pancreas.</description><subject>Animals</subject><subject>beta Catenin - metabolism</subject><subject>Binding</subject><subject>Biology</subject><subject>Bioscience</subject><subject>Calcium</subject><subject>Cancer</subject><subject>Cell</subject><subject>Cycle</subject><subject>Gene Expression Regulation, Developmental</subject><subject>Gene Expression Regulation, Neoplastic</subject><subject>Humans</subject><subject>Landes</subject><subject>Organogenesis</subject><subject>Pancreas - embryology</subject><subject>Pancreatic Neoplasms - metabolism</subject><subject>Pancreatic Neoplasms - pathology</subject><subject>Proteins</subject><subject>Wnt Proteins - metabolism</subject><issn>1538-4101</issn><issn>1551-4005</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkD1PwzAQhi0EoqUwsaNMLCipL3bshA2Fr0qVYAAxWq59kYLyUewE1L_FD-E3kSoFFqY76Z577_QQcgo04iBgbkyURBDFccb2yBSSBEJOabK_7VkacqAwIUfev1IapzKDQzIBweJYZPGUpI-6MQ61D67xHat2XWPTBbqxQT4M0F0GL003__oMc91hUzaB7oKF9z0ek4NCVx5PdnVGnm9vnvL7cPlwt8ivlqHhAF0oBQBDTalMYqoppwwYRy5sUWQ0g8IIxqnUwlJjdZFYSKUEnaKRaZJahmxGzsfctWvfevSdqktvsKp0g23vlZCCplzCAF6MoHGt9w4LtXZlrd1GAVVbUcoYlShQW1EDfbaL7Vc12j92Z2YA5iMwHLLoV2XrTYmDkl90iNOuK02FP5Fi3CibonW1_mhdZVWnN1XrCjfYLL1i__3yDb5Ihdw</recordid><startdate>20060101</startdate><enddate>20060101</enddate><creator>Dessimoz, Jessica</creator><creator>Grapin-Botton, Anne</creator><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20060101</creationdate><title>Pancreas Development and Cancer: Wnt/β-Catenin at Issue</title><author>Dessimoz, Jessica ; Grapin-Botton, Anne</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c411t-76113ea007520a0403134e46dff9091fc63407a6d0cdaf5d18771a8ec7858d3e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Animals</topic><topic>beta Catenin - metabolism</topic><topic>Binding</topic><topic>Biology</topic><topic>Bioscience</topic><topic>Calcium</topic><topic>Cancer</topic><topic>Cell</topic><topic>Cycle</topic><topic>Gene Expression Regulation, Developmental</topic><topic>Gene Expression Regulation, Neoplastic</topic><topic>Humans</topic><topic>Landes</topic><topic>Organogenesis</topic><topic>Pancreas - embryology</topic><topic>Pancreatic Neoplasms - metabolism</topic><topic>Pancreatic Neoplasms - pathology</topic><topic>Proteins</topic><topic>Wnt Proteins - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dessimoz, Jessica</creatorcontrib><creatorcontrib>Grapin-Botton, Anne</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cell cycle (Georgetown, Tex.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dessimoz, Jessica</au><au>Grapin-Botton, Anne</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pancreas Development and Cancer: Wnt/β-Catenin at Issue</atitle><jtitle>Cell cycle (Georgetown, Tex.)</jtitle><addtitle>Cell Cycle</addtitle><date>2006-01-01</date><risdate>2006</risdate><volume>5</volume><issue>1</issue><spage>7</spage><epage>10</epage><pages>7-10</pages><issn>1538-4101</issn><eissn>1551-4005</eissn><abstract>β-catenin and Adenomatous poliposis coli (APC) have been implicated in non-ductal pancreatic cancers. 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| ispartof | Cell cycle (Georgetown, Tex.), 2006-01, Vol.5 (1), p.7-10 |
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| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Animals beta Catenin - metabolism Binding Biology Bioscience Calcium Cancer Cell Cycle Gene Expression Regulation, Developmental Gene Expression Regulation, Neoplastic Humans Landes Organogenesis Pancreas - embryology Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - pathology Proteins Wnt Proteins - metabolism |
| title | Pancreas Development and Cancer: Wnt/β-Catenin at Issue |
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