The Arf Tumor Suppressor Regulates Platelet-Derived Growth Factor Receptor ? Signaling: A New View through the Eyes of Arf-/- Mice

Arf is a key mammalian tumor suppressor gene known to be activated in response to aberrant mitogenic signals leading to both p53-dependent and -independent effects. We recently uncovered a new and somewhat unexpected function for mouse Arf as a regulator of mural cell accumulation within an ocular v...

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Veröffentlicht in:Cell cycle (Georgetown, Tex.) Tex.), 2005-10, Vol.4 (10), p.1316-1319
Hauptverfasser: Thornton, J. Derek, Silva, Ricardo L.A., Martin, Amy C., Skapek, Stephen X.
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Sprache:eng
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