The First 30 Minutes in the Life of a Virus: unREST in the Nucleus

On entry of viral DNA into cells, a competition ensues between cellular factors that silence viral genes and transcriptional factors that block silencing and transcribe the DNA. In the case of herpes simplex virus 1, the first set of genes expressed after infection - are induced by a viral protein (...

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Veröffentlicht in:	Cell cycle (Georgetown, Tex.) Tex.), 2005-08, Vol.4 (8), p.1019-1021
Hauptverfasser:	Roizman, Bernard, Gu, Haidong, Mandel, Gail
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Biology Bioscience Calcium Cancer Cell Cell Nucleus - metabolism Cycle Cytoplasm - metabolism DNA Viruses DNA, Viral Exons Gene Silencing Genome, Viral Herpesvirus 1, Human - metabolism Histone Deacetylase 1 Histone Deacetylase 2 Histone Deacetylases - metabolism Humans Immediate-Early Proteins - chemistry Immediate-Early Proteins - metabolism Landes Models, Biological Mutation Neurons - metabolism Organogenesis Phosphorylation Protein Transport Proteins Repressor Proteins - metabolism Time Factors Transcriptional Activation Ubiquitin-Protein Ligases - chemistry
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