Dok1 and SHIP Act as Negative Regulators of v-Abl-Induced Pre-B Cell Transformation, Proliferation and Ras/Erk Activation

The v-Abl tyrosine kinase activates several signaling pathways during transformation of bonemarrow cells in mice. Because the SH2-containing inositol 5'-phosphatase (SHIP) andDownstream of tyrosine kinase 1 (Dok1) have been shown interact with Abl, the effect ofSHIP and Dok1 deficiency on v-Abl...

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Veröffentlicht in:	Cell cycle (Georgetown, Tex.) Tex.), 2005-02, Vol.4 (2), p.309-313
Hauptverfasser:	Oki, Shinji, Limnander, André, Yao, Pin Mei, Niki, Masaru, Pandolfi, Pier P., Rothman, Paul B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Biology Bioscience Calcium Cancer Cell Cycle Landes Organogenesis Proteins
Online-Zugang:	Volltext
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