Polyploidy and liver proliferation: Central role of insulin signaling

The formation of polyploid cells is part of the developmental program in several tissues. Polyploidy is a characteristic feature of mammalian hepatocytes and it is emerging that this process is an important mechanism of restricting liver growth. We previously demonstrated that during post-natal deve...

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Veröffentlicht in:Cell cycle (Georgetown, Tex.) Tex.), 2010-02, Vol.9 (3), p.460-466
Hauptverfasser: Celton-Morizur, Séverine, Merlen, Grégory, Couton, Dominique, Desdouets, Chantal
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Sprache:eng
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