Adaptation of a chemosensitivity assay to accurately assess pemetrexed in ex vivo cultures of lung cancer

Purpose: Pemetrexed is the only FDA approved treatment for mesothelioma and is a second line agent for treatment of non-small cell lung carcinoma (NSCLC). Pemetrexed is inhibited by folate and its analogs, which are components of many culture media, making it challenging to study pemetrexed in vitro...

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Veröffentlicht in:	Cancer biology & therapy 2013-01, Vol.14 (1), p.0-1
Hauptverfasser:	Stacey L. Brower, Matthew J. Schuchert, Rodney J. Landreneau, Sarah L. Suchy, Dakun Wang, Paul R. Ervin, Jr
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Biology Bioscience Calcium Cancer Cell Cycle Landes Organogenesis Proteins
Online-Zugang:	Volltext
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