Pharmacogene expression during progression of metabolic dysfunction-associated steatotic liver disease: Studies on mRNA and protein levels and their relevance to drug treatment

Metabolic dysfunction-associated steatotic liver disease (MASLD) is common worldwide. Genes and proteins contributing to drug disposition may show altered expression as MASLD progresses. To assess this further, we undertook transcriptomic and proteomic analysis of 137 pharmacogenes in liver biopsies...

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Veröffentlicht in:	BIOCHEMICAL PHARMACOLOGY 2024-10, Vol.228
Hauptverfasser:	Govaere, Olivier, Cockell, Simon J, Zatorska, Michalina, Wonders, Kristy, Tiniakos, Dina, Frey, Andrew M, Palmowksi, Pawel, Walker, Ruth, Porter, Andrew, Trost, Matthias, Anstee, Quentin M, Daly, Ann K
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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