Interobserver Variation in the Assessment of Immunohistochemistry Expression Levels in HER2-Negative Breast Cancer: Can We Improve the Identification of Low Levels of HER2 Expression by Adjusting the Criteria? An International Interobserver Study

The classification of human epidermal growth factor receptor 2 (HER2) expression is optimized to detect HER2-amplified breast cancer (BC). However, novel HER2-targeting agents are also effective for BCs with low levels of HER2. This raises the question whether the current guidelines for HER2 testing...

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Veröffentlicht in:	MODERN PATHOLOGY 2023-01, Vol.36 (1)
Hauptverfasser:	Baez-Navarro, Ximena, van Bockstal, Mieke R, Nawawi, Dienna, Broeckx, Glenn, Colpaert, Cecile, Doebar, Shusma C, Hogenes, Marieke C.H, Koop, Esther, Lambein, Kathleen, Peeters, Dieter J.E, Sinke, Renata H.J.A, van Brakel, Johannes Bastiaan, van der Starre-Gaal, Jose, van der Vegt, Bert, van de Vijver, Koen, Vreuls, Celien P.H, Vreuls, Willem, Westenend, Pieter J, van Deurzen, Carolien H.M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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