Dose optimization of β-lactam antibiotics in children: from population pharmacokinetics to individualized therapy

INTRODUCTION: β-Lactams are the most widely used antibiotics in children. Their optimal dosing is essential to maximize their efficacy, while minimizing the risk for toxicity and the further emergence of antimicrobial resistance. However, most β-lactams were developed and licensed long before regula...

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Veröffentlicht in:	EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY 2024-08, Vol.20 (8), p.787-804
Hauptverfasser:	Ngougni Pokem, Perrin, Vanneste, Dorian, Schouwenburg, Stef, Abdulla, Alan, Gijsen, Matthias, Dhont, Evelyn, van der Linden, Dimitri, Spriet, Isabel, De Cock, Pieter, Koch, Birgit, Van Bambeke, Francoise, Wijnant, Gert-Jan
Format:	Artikel
Sprache:	eng
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