The Impact of Peptidyl Arginine Deiminase 4-Dependent Neutrophil Extracellular Trap Formation on the Early Development of Intestinal Fibrosis in Crohn's Disease

BACKGROUND AND AIMS: During early phases of inflammation, activated neutrophils extrude neutrophil extracellular traps (NETs) in a PAD4-dependent manner, aggravating tissue injury and remodelling. In this study, we investigated the potential pro-fibrotic properties and signalling of NETs in Crohn�...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	JOURNAL OF CROHNS & COLITIS 2024-08
Hauptverfasser:	Dragoni, Gabriele, Ke, Bo-Jun, Picariello, Lucia, Abdurahiman, Saeed, Ceni, Elisabetta, Biscu, Francesca, Mello, Tommaso, Polvani, Simone, Innocenti, Tommaso, Spalart, Valerie, Milani, Stefano, D'Hoore, Andre, Bislenghi, Gabriele, Scaringi, Stefano, Verstockt, Bram, De Hertogh, Gert, Martinod, Kimberly, Galli, Andrea, Matteoli, Gianluca, Vermeire, Severine
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!