Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals

The transcription factor Sip1 (Zeb2) plays multiple roles during CNS development from early acquisition of neural fate to cortical neurogenesis and gliogenesis. In humans, SIP1 (ZEB2) haploinsufficiency leads to Mowat-Wilson syndrome, a complex congenital anomaly including intellectual disability, e...

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Veröffentlicht in:Development 2016-08, Vol.143 (15), p.2829-2841
Hauptverfasser: Menuchin-Lasowski, Yotam, Oren-Giladi, Pazit, Xie, Qing, Ezra-Elia, Raaya, Ofri, Ron, Peled-Hajaj, Shany, Farhy, Chen, Higashi, Yujiro, Van de Putte, Tom, Kondoh, Hisato, Huylebroeck, Danny, Cvekl, Ales, Ashery-Padan, Ruth
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Sprache:eng
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