microRNA-132 regulates gene expression programs involved in microglial homeostasis

microRNA-132 (miR-132), a known neuronal regulator, is one of the most robustly downregulated microRNAs (miRNAs) in the brain of Alzheimer's disease (AD) patients. Increasing miR-132 in AD mouse brain ameliorates amyloid and Tau pathologies, and also restores adult hippocampal neurogenesis and...

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Veröffentlicht in:	ISCIENCE 2023-06, Vol.26 (6)
Hauptverfasser:	Walgrave, Hannah, Penning, Amber, Tosoni, Giorgia, Snoeck, Sarah, Davie, Kristofer, Davis, Emma, Wolfs, Leen, Sierksma, Annerieke, Mars, Mayte, Bu, Taofeng, Thrupp, Nicola, Zhou, Lujia, Moechars, Diederik, Mancuso, Renzo, Fiers, Mark, Howden, Andrew J.M, De Strooper, Bart, Salta, Evgenia
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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