GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation

Nitric oxide (NO) production in the tumor microenvironment is a common element in cancer. S-nitrosylation, the post-translational modification of cysteines by NO, is emerging as a key transduction mechanism sustaining tumorigenesis. However, most oncoproteins that are regulated by S-nitrosylation ar...

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Veröffentlicht in:CELL REPORTS 2023-01, Vol.42 (1)
Hauptverfasser: Rizza, Salvatore, Leo, Luca Di, Pecorari, Chiara, Giglio, Paola, Faienza, Fiorella, Montagna, Costanza, Maiani, Emiliano, Puglia, Michele, Bosisio, Francesca M, Petersen, Trine Skov, Lin, Lin, Rissler, Vendela, Viloria, Juan Salamanca, Luo, Yonglun, Papaleo, Elena, De Zio, Daniela, Blagoev, Blagoy, Filomeni, Giuseppe
Format: Artikel
Sprache:eng
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