EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation

Neuronal activity causes use-dependent decline in protein function. However, it is unclear how this is coupled to local quality control mechanisms. We show in Drosophila that the endocytic protein Endophilin-A (EndoA) connects activity-induced calcium influx to synaptic autophagy and neuronal surviv...

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Veröffentlicht in:	NEURON 2023-05, Vol.111 (9), p.1402-+
Hauptverfasser:	Bademosi, Adekunle T, Decet, Marianna, Kuenen, Sabine, Calatayud, Carles, Swerts, Jef, Gallego, Sandra F, Schoovaerts, Nils, Karamanou, Spyridoula, Louros, Nikolaos, Martin, Ella, Sibarita, Jean-Baptiste, Vints, Katlijn, Gounko, Natalia V, Meunier, Frederic A, Economou, Anastassios, Versees, Wim, Rousseau, Frederic, Schymkowitz, Joost, Soukup, Sandra-F, Verstreken, Patrik
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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