CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer

Cancer-associated fibroblasts (CAFs) are abundantly present in the microenvironment of virtually all tumors and strongly impact tumor progression. Despite increasing insight into their function and heterogeneity, little is known regarding the origin of CAFs. Understanding the origin of CAF heterogen...

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Veröffentlicht in:NATURE COMMUNICATIONS 2023-01, Vol.14 (1)
Hauptverfasser: Houthuijzen, Julia M, de Bruijn, Roebi, van der Burg, Eline, Drenth, Anne Paulien, Wientjens, Ellen, Filipovic, Tamara, Bullock, Esme, Brambillasca, Chiara S, Pulver, Emilia M, Nieuwland, Marja, de Rink, Iris, van Diepen, Frank, Klarenbeek, Sjoerd, Kerkhoven, Ron, Brunton, Valerie G, Scheele, Colinda L.G.J, Boelens, Mirjam C, Jonkers, Jos
Format: Artikel
Sprache:eng
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