Butyrate ameliorates caerulein-induced acute pancreatitis and associated intestinal injury by tissue-specific mechanisms

BACKGROUND AND PURPOSE: Acute pancreatitis (AP) is a common acute abdominal condition, frequently associated with intestinal barrier dysfunction, which aggravates AP retroactively. Butyrate exhibits anti-inflammatory effects in a variety of inflammatory diseases. However, its potential beneficial ef...

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Veröffentlicht in:BRITISH JOURNAL OF PHARMACOLOGY 2019-12, Vol.176 (23), p.4446-4461
Hauptverfasser: Pan, Xiaohua, Fang, Xin, Wang, Fei, Li, Hongli, Niu, Wenying, Liang, Wenjie, Wu, Chengfei, Li, Jiahong, Tu, Xing, Pan, Li-Long, Sun, Jia
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Sprache:eng
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