Comparing in vivo bioluminescence imaging and the Multi-Cruzi immunoassay platform to develop improved Chagas disease diagnostic procedures and biomarkers for monitoring parasitological cure

BACKGROUND: Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and is a serious public health problem throughout Latin America. With 6 million people infected, there is a major international effort to develop new drugs. In the chronic phase of the disease, the parasite burden is ex...

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Veröffentlicht in:PLOS NEGLECTED TROPICAL DISEASES 2022-10, Vol.16 (10)
Hauptverfasser: Francisco, Amanda Fortes, Saade, Ursula, Jayawardhana, Shiromani, Pottel, Hans, Scandale, Ivan, Chatelain, Eric, Liehl, Peter, Kelly, John M, Zrein, Maan
Format: Artikel
Sprache:eng
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